A comparative study found that hospitalized Covid-19 patients had fewer comorbidities than influenza patients-health

A comparative study of inpatient coronavirus and flu patients found that Covid-19 patients had fewer comorbidities and used less medication than flu patients.

This study was conducted in patients in the United States and Spain.

It was published by the Observational Health Data Sciences and Informatics (OHDSI) community.

OHDSI, along with the Central Coordinating Center at Columbia University’s Faculty of Biomedical Informatics, has established an international network of researchers and observational health databases.

This global network study of more than 34,000 Covid-19 patients across three continents provides a more detailed description of the characteristics of patients suffering from the disease and informs inpatient care decisions. I am aiming.

Nature Communications has published a study entitled “The Deep Phenotype of 34,128 Adult Patients Admitted to Covid-19 in an International Network Study.”

Patients hospitalized for Covid-19 were more commonly male in the United States and Spain, but more often female in South Korea. Patients varied in age, but in Spain and the United States, the most common age group was 60-75 years. Patients hospitalized for influenza were usually older and more likely to be female than those hospitalized for Covid-19.

Many patients admitted with Covid-19 were found to be in other health conditions. For example, across data sources, the prevalence of hypertensive disorders ranged from 24% to 70%, diabetes from 13% to 43%, and asthma from 4% to 15%. However, despite this, Covid-19 patients were generally seen to be healthy when compared to those who were recently hospitalized for influenza. Chronic obstructive pulmonary disease (COPD), cardiovascular disease, and dementia were all more common in patients hospitalized for influenza than in patients hospitalized for Covid-19. “This study provided a better understanding of the profile of patients admitted to Covid-19,” says co-author Edward Burn. “Despite recent debates about poor health and life expectancy limits for Covid-19 patients, Covid-19 patients are not in poorer health than those who are usually hospitalized for influenza. It further emphasizes the high mortality rate of Covid-19 patients. “

The study began during the 88-hour global interdisciplinary collaboration OHDSI Covid-19 Stadiatone. The first Covid-19 data, provided by the Korean Health Insurance Review and Assessment Service (HIRA), empowered the community to generate some of the early multinational studies during the pandemic. All analysis is performed at individual sites. This means you don’t have to share patient-level data to maintain patient privacy.

“The most interesting part of this study was that we were able to provide patient characteristic details across the facility without compromising privacy,” said co-author, who led the effort to map HIRA data to OHDSI. Said Seng Chan You. Common data model. “It’s important to know that this is possible because we don’t know what’s coming next. When is the next pandemic? No matter what happens, we provide important patient characteristics and collaborate. I know that it can enable global research in. “

This study was developed and carried out by the OHDSI community, an interdisciplinary collaboration of multiple stakeholders that serves to unlock the value of health data through extensive analysis. All solutions are open source and have links to research protocols, code, and results in the paper.

“Open science and collaboration are the beliefs of the OHDSI community and have never been more important than in the early days of this pandemic,” said Patrick Ryan, co-author of the study. “Our community has worked together over the years to develop high-level analyses that set the course for these studies. Due to our belief in sharing patient data openly, this reliability Generates highly reproducible Covid patient data to assist in important decisions. We will fight this disease. “

“This study is the foundational work for future joint evidence generation by both OHDSI and the EHDEN Consortium mapping additional Covid data across Europe,” said co-lead author Daniel Priet Alhambra. I am. “Overall baseline demographics, clinical features, treatments and outcomes of Covid-19 patients and stratification by gender, age, and specific comorbidities can be of great help in making decisions in this pandemic. We are collaborating globally on these studies. “

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