Researchers at Stony Brook University found that the first World Trade Center responders who inhaled toxic dust after the 9/11 terrorist attacks were at high risk of cognitive decline and early-onset dementia. Received a federal grant of $ 7.9 million to evaluate.
A five-year grant from the National Institute on Aging examines evidence of brain biomarkers similar to Alzheimer’s disease in more than 1,000 first responders treated by the university’s WTC Health and Wellness Program.
According to university officials, this is the first and only cognitive monitoring study on Ground Zero first responders.
“Overall, the first responders at the World Trade Center are experiencing cognitive decline and cognitive impairment that are rare in this age group,” said Stony Brook, an associate professor of family, population, and preventive medicine, who leads the study. One Sean Clawston said. “At least 10 years early”
Researchers also found that cognitive decline in patients is affected by both post-traumatic stress disorders, a common illness among the first responders to Ground Zero, and toxic chemicals that float in southern Manhattan after a terrorist attack. Investigate whether you received it.
Over the past five years, Dr. Benjamin Luft, director of Clouston and the Health and Wellness Program and collaborator in grant research, has conducted memory and cognitive tests on 1,000 first responders.
It the studyReleased this summer, about 15% of the first respondents in 9/11 showed signs of cognitive impairment at about three times the general population of the age group.
Studies also show that the first responders who later develop post-traumatic stress syndrome may exhibit neurological abnormalities and blood changes, as do patients with Alzheimer’s disease and associated dementia. it was high. The researchers found that the average brain “age” of the first respondents, who showed signs of cognitive impairment, appeared to be about 7-10 years older than the normal population.
The new study will track biomarkers that are thought to predict cognitive dysfunction in the same patient, and will continue and extend previous studies, Clawston said. Blood and urine are collected from the patient, and researchers perform brain imaging scans to determine if the cognitive impairment is Alzheimer’s disease or another.
In the aftermath of the attack, an estimated 500,000 people, including nearly 100,000 first responders, could have been exposed to environmental pollutants. Many were later diagnosed with a range of cancers and respiratory illnesses, including asthma, chronic obstructive pulmonary disease (more commonly referred to as COPD), and interstitial lung disease.
“If successful, you will be able to determine if it is PTSD or PTSD. [WTC] Exposure is associated with things like Alzheimer’s disease, “Crowston said. “And you should be able to better understand what the exact biomarkers for monitoring are, so if people need to be tested … we should be able to recommend testing.”
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