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Loss of odor is an indicator of asymptomatic cases: study

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IISER researchers Measure Smell Function to detect COVID patients Those who show no other signs

Pune’s new study by researchers at the Institute for Scientific Education (IISER) has identified a way to measure the olfactory function of people who claim to be able to detect asymptomatic COVID-19 infections caused by SARS. Reported-CoV-2 virus.

Given that asymptomatic patients are asymptomatic carriers of the disease, a paper published in Lancet’s EClinical Medicinetalks describes an individual’s olfactory observations. Researchers have suggested that it helps detect if the novel is infected. Coronavirus..

This paper studies anosmia (loss of olfaction) and hypoolfaction (decreased olfaction) in asymptomatic COVID-19 patients.

The study was conducted by Dr. Nixon Abraham, a IISER faculty member who started the study during the blockade.

Talking about the project Dr. Abraham “We focused on odor measurement and tried to find out how even amateurs could detect odor loss and identify if they were infected with the virus. Anosmia is for detecting COVID-19. It’s a marker, but it gradually develops in patients. ”

As more information about the new pandemic began to emerge, many patients reported loss of odor as a side effect of being infected with the virus.

Dr. Abraham’s work revolves around the neural circuits that mediate olfactory-driven behavior.

Along with PhD student Anindya Bhattacharjee, Dr. Abraham tested whether anosmia / hyposmia could be an indicator of COVID-19 in individuals who are virus-positive but do not show other typical symptoms. I started.

The duo was able to collect more than 3,600 readings from 71 subjects, including normal healthy subjects and asymptomatic COVID-19 patients, using odorants with various physicochemical properties. It was.

Using this screening method, the team analyzed detection indicators at different odor concentrations and olfactory matching capabilities across different odorants.

“This process was able to generate a unique olfactory function score for each individual tested,” said Batacharji, who made these measurements at BJ Medical College with Dr. Abraham.

He added: parameter The olfaction of asymptomatic COVID-19 patients admitted to the hospital was subsequently evaluated for normal healthy subjects.

With our optimized method, olfactory dysfunction was identified in 82% of asymptomatic COVID-19 carriers. By comparison, only 15% of the same patient set reported olfactory loss in the self-reporting paradigm. ”

Dr. Abraham talks about how individuals can measure whether or not they have olfactory dysfunction, saying: You can test by diluting the strong odor with water.Can also be used asthma The inhaler pump forms a unique detection tool to monitor odor loss. If there is a change in odor levels, you can be tested for COVID-19. ”

Dr. Abraham feels that this study laid the necessary foundation for considering olfactory health as one of the key criteria for identifying COVID-19 asymptomatic carriers. “The methods and parameters established by our research could be transformed into sensitive, fast and economical olfactory-based screening methods that more people can self-manage,” the researchers claim. I will.

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