Health
Tobacco is used as a key ingredient in some coronavirus vaccines
Throughout history, indigenous peoples of North America and Alaska have worshiped tobacco plants for use in medical practice, in addition to using them in spiritual rituals.But in recent years, this plant has been badly named for the use of one tobacco strain called Nicothiana Tabakam To make tobacco.
According to the US Centers for Disease Control and Prevention, this particular strain is one of at least 70 known tobacco strains, killing more than 480,000 people annually.
“There’s a clear irony there,” said James Figurer, Executive Vice President of Research and Development at RJ Reynolds Tobacco. Reynolds owns KBP.
“If you want to be cynical about it, you can,” Figler said. “But we tend to think of it as the end of the day. The tobacco plant itself is still just a plant.”
According to the CDC, the vaccine works by mimicking an infection, convincing the immune system that it has been exposed to a pathogen, and causing the immune system to produce T lymphocytes and antibodies.
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There are multiple ways to do this. One of them is to introduce something into the immune system that looks like a virus but is not infectious. This approach is used by Kentucky Bioprocessing.
Seven days after the plant is infected by the soaking process, it goes through an extraction and purification process.
“At the end of the cycle, we have 99.9 percent pure protein,” KBP President Hugh Haydon told NPR.
Another set of plants produces small particles for packaging viral proteins. Both separately manufactured and packaged components then chemically adhere.
The final product, which can be injected into humans as a vaccine, is expected to stimulate an immune response that would theoretically protect someone from death from the coronavirus.
“So when it appears in the body, it looks like a virus and produces a reaction, but it has no genetic material inside,” so it can’t really infect anyone, Clark said. Said.
According to KBP, one of the advantages of vaccines is that they can be stored at room temperature, unlike traditional vaccines, which often require refrigeration, which is a major advantage over other vaccines.
KBP is a unit that develops vaccines for British American Tobacco BATS.L, a manufacturer of dunhill and Lucky Strike cigarettes. They announced that they had begun manufacturing the vaccine in April and announced that they would work with the U.S. Food and Drug Administration and the UK health authorities to bring the vaccine to clinical trials as soon as possible in the next step. did.
“We believe we have made great strides in the tobacco plant technology platform and are ready to work with the government and all stakeholders to win the battle against COVID-19,” said BAT’s scientific research. Director David O’Reilly said. Said in a statement.
KBP was mentioned a few years ago that it worked with California-based Map Biopharmaceuticals to create an effective treatment for Ebola called ZMapp.
Reuters contributed to this report.
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