Health

Temple University School of Medicine Luis Katz Helps Identify Cytokine Storms in COVID-19 Patients

Philadelphia (WPVI)-A new study from Temple University’s Lewis Katz School of Medicine has helped identify patients at greater risk for one of the most life-threatening reactions to COVID-19.

Dr. Roberto Carricchio, lead author of recent studies, states that further research is needed, but their data and criteria are now available online and accessible for free. Other healthcare centers can use this information to perform their own lab tests, further validate the criteria, and use it to make decisions about treating patients.

At least 20% of inpatients with COVID-19 can suffer from serious and sometimes fatal complications. However, it is difficult to predict who those patients will be until it is too late.

One of those complications is known as a cytokine storm. This is an immune hyperreactivity that leads to massive inflammation and organ closure.

“It can be the kidneys along with the lungs. It can be the heart along with the lungs, or it can be the heart and liver, so it’s multiple organ failure,” Carricchio said. It was.

He says it’s hard to turn around once it starts to happen. So he and other researchers at Temple University studied laboratory work and image scans of hundreds of patients, focusing on criteria that could predict patients at risk before suffering from symptoms.

Subsequent studies have shown that the algorithms they create can predict cytokine storms in up to 85% of cases. After that, treatment can be given early, increasing the patient’s chances of survival.

Dr. Caricchio states that steroids and some drugs that are still in clinical trials can be more aggressive.

“A drug that would not be given otherwise,” he said.
He says further research is needed, but their research and standards are now published online. Annual report of rheumatoid arthritis..

Other medical centers can perform the same tests to further validate the criteria and use them to make treatment decisions.

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