Health
Is it worse than illness? Scientists warn that some Covid-19 vaccines may increase the risk of HIV — RT World News
A group of researchers in the United States have warned about some coronavirus vaccines currently in clinical trials, warning that subjects taking them may be at increased risk of becoming infected with HIV. I am.
According to a team of scientists led by Susan Buchbinder, a professor at the University of California, San Francisco and head of HIV, at least four of the current batches of the Covid-19 vaccine under development in clinical trials have patients with HIV. It may increase the risk of infection. Preventive research at the San Francisco School of Public Health. One of the vaccines is at stake in Phase 3 trials in Russia and Pakistan.
Buchbinder and her colleagues have directly experienced the side effects of this particular vaccine from previous studies on the HIV vaccine. Their most promising candidate vaccines had the opposite effect of what they wanted, making people even more susceptible to illness than before.
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“We are concerned that the use of the Ad5 vector for vaccination against SARS-CoV-2 may also increase the risk of acquiring HIV-1 in vaccinated men.” they I have written..
Vectors are a way to deliver a vaccine to a target location. One of the more common vectors used in medical research is genetically modified adenovirus. This is usually a group of DNA viruses that cause eye and respiratory illness.
Some of the current batches of Covid-19 vaccine under development are adenovirus as a method of delivering the genetic code of the coronavirus spike protein with the aim of training the immune system to recognize and repel SARS-CoV-2. using.
Genetically modified adenoviruses, often used as vectors, do not increase the risk of HIV.
However, a particular one, called Ad5 (Recombinant Adenovirus Type 5), is the culprit who reverted the previous HIV vaccine of Buchbinder and her team and is at the center of the current vaccine controversy.
The mechanism by which it increases the risk of becoming infected with HIV is not well understood, but it provides more targets for HIV than before and stimulates the immune system to gain a foothold in the body much faster. It seems.
Immunologist Anthony Fauci, who has been the director of the National Institute of Allergy and Infectious Diseases since 1984, decided to use this particular vector in vaccines distributed to areas at risk for HIV in 2014. I warned against it.
Nonetheless, the companies behind the vaccine in question claim to be aware of the problem and take risks into account during vaccine development.
For example, Immunity Bio, which is currently testing the vaccine in California before the next step in South Africa, claimed to have genetically “mutated” the vaccine’s Ad5 vector.
Some vaccine trials have already been suspended due to adverse side effects and death in one case.
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