Studies have shown that asymptomatic children have lower coronavirus levels than symptomatic children

The researchers also pointed out that the levels of the virus found in asymptomatic children were much lower than those detected by the rapid antigen tests available. (Photo courtesy of IE)

Analysis of more than 800 pediatric cases of coronavirus infection revealed that most asymptomatic children have significantly lower levels of the virus than children who experience symptoms.

However, the study, published in the Journal of Clinical Microbiology, warned that the reason for this discovery was unknown, but did not explain how reduced viral load affects the risk of COVID-19 infection. Hmm.

“These findings provide some reassurance about the safety of children with asymptomatic infections in school, but these unanswered questions are day care to reduce the prevalence of COVID-19. It suggests that risk mitigation measures in schools, schools, and communities remain important, “said Larry Kosiolek, lead author of the study. , US Ann & Robert H. Lurie Children’s Hospital Pediatric Infectious Diseases Specialist.

“Children need to keep wearing masks, stay socially distant, and wash their hands frequently,” Kociolek said.
According to scientists, it is still difficult to predict which children are more or less likely to carry the virus.

“There were some asymptomatic children with high viral load in all age groups we tested, but even the group of asymptomatic children with the highest viral load in our study. The viral load was lower than in symptomatic children, “said Kosiolek.

In this study, scientists found 339 asymptomatic and 478 symptomatic children (0-17) screened for COVID-19 positive using PCR tests in nine pediatric hospitals in the United States and Canada. Years old) was evaluated.

The analysis showed that asymptomatic children with recent contact with diabetes and / or COVID-19 cases, and children tested for surveillance purposes, had a significantly higher risk of estimating the highest viral load. ..

According to scientists, this finding suggests that the timing of infection compared to diagnostic tests affected viral load in asymptomatic children in the study. However, they also noted that even in the asymptomatic surveillance subcohort with the highest viral load, the average level of virus was significantly lower than in the symptomatic cohort.

“We need to know the peak viral load in asymptomatic children with COVID-19 — did many of the asymptomatic children in this study just miss the peak timing of the test, or are asymptomatic? Are children with a really low peak viral load? Asymptomatic children? ”Nirapolok, senior author of the study and associate medical director of the Institute for Infectious Diseases Diagnosis at Boston Children’s Hospital in the United States, said.

The researchers also pointed out that the levels of the virus found in asymptomatic children were much lower than those detected by the rapid antigen tests available. “Rapid antigen testing is less sensitive than PCR testing used in hospitals, and many of the asymptomatic children in our study were negative using rapid testing based on an understanding of detection limits. It’s important to recognize that it’s likely. Test them, “said Pollock.

Based on the findings, the researchers cautioned against using low-sensitivity tests in asymptomatic screening programs in pediatric populations.

“Overall, we would like to encourage more research to better understand the viral load in asymptomatic children, especially the early peak viral load of infection,” Pollock added.

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