Pfizer’s Covid-19 vaccine trial transitions to 12-year-old child

The Cincinnati Children’s Hospital team vaccinated 100 children up to the age of 12 last week, said Dr. Robert Frenck, who is leading the Pfizer Covid-19 vaccine trial at the hospital. “We are currently suspending to monitor the response to the vaccine. We are currently suspending a planned suspension to ensure that everything is as safe as possible,” Frenck told CNN. ..

Side effects that doctors are paying attention to include lumps at the injection site, redness, pain, fever and pain.

12-year-old Abhinav is one of the young volunteers.Seventh grade, who asked parents to use only his name to protect his privacy, was extensively vaccinated as his grandparents resumed visits from India and classes returned to normal at school. Hope to help keep you safe

“Everyone in my school wants to go back to normal,” Abhinav told CNN. “I really think the vaccine can prevent the spread of the infection. For now, I’ll probably ask other children to take it.”

Abhinav schools, unlike many schools across the country, offer direct classes. He says the desk is far away with a plexiglass screen among the students. “We wear masks all day,” he said. “That’s kind of weird. If someone is talking from the other side of the classroom, you can’t really hear them through the plexiglass.”

Abhinav knows that there is only a 50% chance that he will actually be vaccinated. Half of the volunteers in this third and final phase of Pfizer’s vaccine have a placebo or dummy shot. But he wants him to get a real shot because he believes the vaccine protects him from infection and thus prevents him from spreading the virus to others.

Abinaf’s father, Sharat, was thinking more about the safety of his child. When asked why he brought Abinaf to trial, he said, “I think it’s mainly to protect my son, and in the process it’s also useful for science. I felt it was something to do.” ..

Sharat, a hospital doctor himself, volunteered for a Phase 1 test of the vaccine earlier this year and was confident that it would not only be safe for his son, but would also prevent the virus from infecting him.

“I know the side effects that affect the AstraZeneca vaccine,” he said. The AstraZeneca trial was suspended in the United States for nearly two months after British volunteers developed neurological symptoms.U.S. trial I got up again last week..

Frenck said people may be nervous about giving children vaccines, but Pfizer has already been tested in tens of thousands of adults.

“The reason this vaccine can be used in children is because Pfizer has 30,000 registered adults and safety data from all of them,” he said.

In addition, he said it is important to vaccinate children with the coronavirus if they wish to control the pandemic. They almost certainly contribute to the silent spread of the virus.

“The important thing people should remember is that adolescents are less ill than older adults, but that doesn’t mean that some children aren’t sick and some aren’t dead. I think that’s the case, “he said.

“To date, 120 children have died of Covid in the United States.”

Pfizer’s vaccine does not use active viruses. It uses a small piece of genetic material called mRNA-the approach originally used to fight cancer. “This is the first time it has been used for infectious diseases,” Frenck said.

Vaccines stimulate the body to make antibodies against spike proteins, the structures used by viruses to attach to attacking cells.

“MRNA is not hanging in the body,” Frenck added. “It deteriorates very quickly.”

So far, the side effects are mild. “Some people feel some pain,” he said. It is possible that the body is building an immune response, similar to the pain caused by a real infection. Of the 400 adults vaccinated in the Cincinnati trial, none missed work due to side effects, Frenck said.

Similarly, volunteer teens responded mildly to vaccination. “One child developed a low-grade fever, took ibuprofen and felt better,” he said.

What about Abinaf? “Now my arms feel pretty good,” he said.

Americans are worried about terms such as warp speed operations and emergency permits, and are worried that vaccines may come out in a hurry.

Frenck doesn’t think so.

He said it was reporting and records management that was happening faster. Reports that typically take weeks to collate and send are run several times a week instead.

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