Deadly levels of radiation exposure can be offset by certain gut bacteria and produce “elite survivors”

A fascinating new study published in Science It claims that certain gut bacteria can offset deadly levels of radiation exposure.This finding is the latest in a series of studies that have suggested that the microbiome has incredible impact. health..

Accidental exposure, radiation therapy for cancer, and targeted radiation attacks have been talked about for many years for their horrific effects on the human body, including illness and death. Accidental exposure claimed the imagination of many, especially after the Chernobyl tragedy in 1986. However, the most common reason behind radiation exposure is due to cancer-related treatments.

“Federal efforts have been made to alleviate acute radiation sickness, but it remains a long-standing problem,” said corresponding author Dr. Jenny PY Ting, Williamland Kenan UNC School of Medicine. Professor of Genetics and Co-Leader of the UNC Lineberger Immunology Program, Science daily..

“Granulocyte colony-stimulating factor is the only drug approved by the FDA for effective treatment of high-dose radiation exposure, but it is expensive and has potential adverse side effects,” said Ting. .. “But the bacteria we can grow, especially the relatively cheap and metabolites already in the food we eat, may be a good option.”

The study found that two common bacteria, available as dietary supplements in many countries, increase the production of small molecules known as propionic acid and tryptophan in mice exposed to deadly levels of radiation. Shown. In addition, the two molecules not only provided protection from radiation, but also enhanced recovery of blood cell production and repair of the gastrointestinal tract.

The author behind the study called people with diverse microbiomes “elite survivors.”

Scientists are optimistic, although it is not yet known if the results will be reflected in humans. Follow-up studies in which bacteria were studied in human patients appeared to show a significant correlation with mice.

“Our research has produced a comprehensive data set of bacteria and metabolites that serve as a powerful resource for identifying practical therapeutic targets in future microbiome research,” said Ting’s lab. Dr. Hao Guo, the first research author to be a postdoctoral researcher, concluded.

In other health-related news, the Geological Society of America recently announced a new mission to tackle the per / polyfluoroalkyl material (PFAS) crisis.As previously covered Inquisitor, Common chemicals are thought to be 140 times more toxic than arsenic, but are found in many daily necessities, such as car wax and fast food wrapping paper.

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