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Mutations in the Covid virus may have made it more contagious: study

Mutations in the Covid virus may have made it more contagious: study

 


The virus that causes Covid-19 has accumulated genetic mutations, one of which may be more contagious, a study of more than 5,000 patients in the United States said.

According to a paper published in the peer-reviewed journal mBIO, the mutation, called D614G, is in a spike protein that breaks open cells for viral invasion.

The patient involved in this study of the SARS-CoV-2 genomic sequence was from Houston, Texas.

“The virus is mutated by a combination of neutral drift (meaning random genetic changes that don’t help or damage the virus) and pressure from the immune system,” said Ilya Finkelstein, an associate professor at the university. “. Co-author of research with Texas in Austin.

During the first wave of the pandemic, 71 percent of the new coronaviruses identified in Houston patients had this mutation.

When the second wave of outbreaks struck Houston during the summer, the variant jumped to a prevalence of 99.9%, the study said, reflecting trends observed around the world. Added.

A study published in July based on more than 28,000 genomic sequences found that mutants with the D614G mutation became the globally predominant form of SARS-CoV-2 in about a month.

SARS-CoV-2 Coronavirus That causes Covid-19.

Fortunately, this mutation is rare and does not appear to make the disease more severe to infected patients.

“The virus continues to mutate as it travels around the world,” Finkelstein said.

“Real-time surveillance efforts like ours will ensure that global vaccines and therapies are always one step ahead.”

Scientists have pointed out a total of 285 mutations across thousands of infections, most of which do not appear to have a significant effect on the severity of the disease.

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