Health
Studies show that SARS-CoV-2 prevents the formation of red blood cells and can cause anemia and organ damage.
In a new study, a group of scientists from the Department of Basic Medicine at the Federal University of the Far East (FEFU) found that COVID-19-related red blood cell damage could be the cause of multi-organ damage in coronavirus patients.
According to their study, it is published in the journal EuroMedica Archive, All viruses target specific types of cells in the body. For example, HIV targets immune system cells, the influenza virus affects the lungs and larynx, and the virus that causes COVID-19 affects multiple organ systems.
Much research has been done to assess the effects of SARS-CoV-2 on the lungs, such as lung cell death and fibrosis, but the authors of the latest study are too much to check for changes in red blood cells. Not performed (RBC) pools (a major target for new coronaviruses) and their effects on COVID-19 patients.
the study
In this study, the researchers evaluated lung biopsy of 11 patients who died of COVID-19 and compared it to a control group of 14 patients who died of life-threatening injuries between the ages of 24 and 76. Did.
A sample from a COVID-19 patient pointed out the following:
- Abnormal (spherical, uneven shape, or smaller or larger than normal shape and size) and sickle cell RBC
- Hemoglobin (an oxygen-carrying protein) heterogeneous distribution in red blood cells
- Thickening of the outer membrane of RBC
- Breakdown of hemolysis or RBC
result
This study showed that the characteristic location of hemoglobin in RBC in COVID-19 patients indicates iron deficiency and B12 anemia. The gastrointestinal effects of SARS-CoV-2 have been suggested to be responsible for the lack of B12.
The type of RBC injury indicates that the virus adversely affects the process of RBC formation, causing iron deficiency and B12 anemia.
The authors of the study also stated that erythrocytes are the main target for SARS-CoV-2. When RBC is lost, ventilation is also useless because the body has difficulty transmitting oxygen to tissues and there is not enough RBC to circulate oxygen. The only way to help such patients is to give them RBC or B12 externally.
The study points out that low hemoglobin levels further increase the risk of tissue damage. This is because in the early stages of the disease, low hemoglobin levels increase the production of erythropoietin, a hormone that helps produce RBC.
This increases the viscosity of the blood and affects the microcirculation (the circulation of blood in the small blood vessels in the tissue). It explains why hypertensive patients are a major risk group for COVID-19 and why erythropoietin-based drugs cannot be used to treat anemia in coronavirus patients.
For more information COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears..
The Firstpost Health article was created by myUpchar.com, India’s first and largest resource for validated medical information. At myUpchar, researchers and journalists work with doctors to provide all the information about health.
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