Studies suggest that melatonin is looking at potential treatments for coronavirus

Melatonin may have more than just helping you get a good night’s sleep.A new study from the Cleveland Clinic suggests that hormones may be a possible treatment option for people infected New coronavirus.

Analyzing patient data from the Cleveland Clinic’s COVID-19 registry, researchers found that melatonin, a hormone that regulates the body’s sleep-wake cycle, “reduces the chances of a SARS-CoV-2 positive test by almost 30%. It is related to letting you do it. ” After adjusting for age, race, smoking history, and various comorbidities. ” According to the news release It accompanies a study published in the journal PLOS Biology. (SARS-CoV-2 is a virus that causes COVID-19.)

Melatonin may have more than just helping you get a good night’s sleep. A new study from the Cleveland Clinic suggests that hormones may be a possible treatment option for people infected with the new coronavirus. (IStock)

The findings on melatonin were derived from each release “a new artificial intelligence platform developed by researchers at the Learner Institute to identify potential drugs for COVID-19 diversion.”

More specifically, the researchers in this study used networked medical methodologies from patients at Cleveland Clinic and large electronic health records to identify clinical symptoms and conditions common to COVID-19 and other diseases. I have identified. “

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Specifically, “they are well associated with host genes / proteins and 64 other diseases across several disease categories (malignant cancer and autoimmunity, cardiovascular, metabolic, neurological and lung diseases). We measured the proximity between and the association between illnesses. ”

For example, in severe cases, respiratory distress syndrome and sepsis have been identified as the two leading causes of death in COVID-19 patients. The proteins associated with these two states were “highly associated with multiple SARS-CoV-2 proteins,” the researchers found.

“It is possible that drugs already approved for the treatment of these respiratory illnesses may also have some usefulness in the treatment of COVID-19 by acting on these shared biological targets. It shows that there is, “explained Dr. Feixiong Cheng, Cleveland’s assistant staff. In the statement, the clinic’s Institute of Genomic Medicine and lead author of research.

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Ultimately, researchers identified autoimmune, lung, and neurological disorders as “significant network proximity to the SARS-CoV-2 gene / protein, identifying 34 drugs as potential diversions. It is mainly melatonin. ”

That said, Chen warned that the researchers’ findings “do not suggest that people should start taking melatonin without consulting a doctor.”

Click here for the full range of coronaviruses

“It is important to validate the clinical benefits of melatonin in patients with COVID-19,” said Chen, who said further studies, especially large observational studies and randomized controlled trials, were needed.

“Recent studies have suggested that COVID-19 is a systematic disease that affects multiple cell types, tissues, and organs, so knowledge of the complex interactions between the virus and other diseases is not available. , The key to understanding COVID-19-related complications and identifying reusable drugs. ” Chen. “Our research provides a powerful and integrated networked healthcare strategy that predicts the symptoms of COVID-19-related diseases and facilitates the search for effective treatments.”

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