Health
Combo “Polypill” May Reduce Heart Attack, Stroke Risk Up to 40%-Consumer Health News
Monday, November 16, 2020 (HealthDay News)-A single pill filled with cholesterol and blood pressure medications can reduce the risk of heart attack and stroke by up to 40%, a new international study reports. ..
According to the results of clinical trials, “Polypill”, which contains three common blood pressure medications and statins, dramatically reduced the risk of heart-related disease in people with no history of heart disease.
Researchers reported that taking Polypill alone reduced the risk of procedures for resuming heart attack, stroke, arterial blockage, and other heart disease by about 20%.
Studies have shown that polypills combined with daily low-dose aspirin are even more effective, reducing heart health problems by up to 40%.
“It is estimated that at least 2-4 million people will avoid premature death, heart attack and stroke each year if treated with such polypills in half of patients with high blood pressure and diabetes,” he said. Dr. Salim Yusuf, a senior researcher who is a professor of medicine at McMaster University in Canada.
There may be other benefits to such a polypill, Yusuf said. It’s easy for patients who don’t have to manage a handful of daily medications or for doctors who only need to write one prescription. Single pills are also cheap to market and distribute.
“Personally, I want the components to be used separately or together. What if it’s more convenient to use them together?” Yusuf said.
The findings were published online on November 13th. New England Journal of Medicine.. In this study, more than 5,700 people from nine countries were randomly assigned to one of four groups. They were asked to take both polypill and aspirin, polypill only, aspirin only, or placebo only daily.
The polypills used in this study included a cholesterol-lowering simvastatin and three blood pressure drugs: a beta-blocker called atenolol, a diuretic called hydrochlorothiazide, and an ACE inhibitor called ramipril.
Compared to placebo, polypills have been successful in lowering blood pressure and cholesterol, researchers found.
Only 4.4% of people who took Polypill alone died of a heart attack, stroke, arterial recanalization, or heart disease, compared to 5.5% who took placebo. Approximately 4.1% of people who took aspirin alone developed heart-related illnesses, compared to 4.7% of people who took placebo.
The combination of polypill and aspirin gave the best results, the study authors said.
The polypill / aspirin combination reduced heart problems and mortality by 31%, the researchers found. People who continued to take the pill without interruption for about four years found that their risk of heart problems was reduced by 40%.
“The combination of aspirin and polypills definitely shows a significant reduction in cardiovascular events,” said Dr. Eugene Yang, chair of the American College of Cardiology’s Cardiovascular Disease Prevention Council.
In the United States, such polypills could be a valuable tool for protecting the heart health of people with low access to health care, according to Yang.
“The medical disparities that exist in this country could benefit US polypills,” Yang said.
Currently, no such cholesterol / blood pressure polypill exists in the United States, Yusuf said.
“The fact that it’s generic is a double-edged sword, because no major pharmaceutical company is willing to invest heavily in the development and marketing of polypills. Health insurance companies, governments, and charities. One develops a polypill. “
Yang also added that doctors may be reluctant to prescribe pills filled with various medications.
“We have all been taught in medical school that we need to administer one drug at a time and see what it does before adding a second drug,” Yang said. Stated.
According to Yang, the study was 95% funded by charities such as Wellcome Trust UK and government agencies. The Indian company Cadila Pharmaceuticals provided 5% of the funding, including the manufacture and distribution of polypills.
Researchers announced their findings at this year’s virtual conference of the American Heart Association over the weekend.
For more information
Harvard Medical School Polypill..
Source: Salim Yusuf, MD, DPhil, Professor, Medicine, McMaster University, Hamilton, Ontario, Canada. Eugene Yang, MD, Chairman of the Cardiovascular Disease Prevention Council of the American College of Cardiology. New England Journal of Medicine, November 13, 2020, online
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
Pictures Credit
to request, modification Contact us at Here or [email protected]
 |
 |
 |
