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China’s COVID Vaccine Looks Safe and Effective-Consumer Health News

China’s COVID Vaccine Looks Safe and Effective-Consumer Health News

 


Wednesday, November 18, 2020 (HealthDay News)-China’s COVID-19 vaccine appears to be safe and effective, with early test results suggesting, but one expert carefully reviews the findings It states that it needs to be done.

The CoronaVac vaccine is based on the inactivated SARS-CoV-2 virus. It was tested in a Phase 1/2 clinical trial involving more than 700 healthy volunteers aged 18-59 years recruited in China between April 16th and May 5th.

The vaccine appeared to be safe and tolerated at all doses tested, the researchers reported. The most common side effect reported was pain at the injection site.

Even at the lowest dose tested (3 micrograms), participants showed strong antibody responses within 2 weeks of the second and final doses. Shots were given every 14 days.

The levels of antibodies caused by the vaccine were lower than those of patients with recovered coronavirus, but researchers said they still believed that the vaccine could provide protection from the virus.

They said the main purpose of the study was to evaluate the immune response and safety of the vaccine. The vaccine is not designed to assess how effective it is in preventing SARS-CoV-2 infection.

Survey results were released on November 17th Lancet infection journal.

After considering side effects and other factors, the researchers determined that a dose of 3 mcg stimulated the best antibody response. This will be further investigated in the ongoing Phase 3 trial.

“Our findings show that CoronaVac can elicit a rapid antibody response within 4 weeks of immunization by administering the vaccine twice at 14-day intervals, which makes the vaccine an emergency during a pandemic. I think it’s suitable for use. ” Fengcai Zhu, co-author of the Centers for Disease Control and Prevention in Jiangsu Province, Nanjing, China.

“In the long run, if the risk of COVID-19 is low, two doses at one-month intervals rather than two-week intervals may be stronger and potentially longer lasting. Immune response, but more research is needed to see how long the antibody response lasts after any vaccination schedule, “Zhu said in a news release in the journal.

CoronaVac is one of 48 COVID-19 vaccine candidates currently in clinical trials.

Naor Bar-Zeev, an associate professor of global disease epidemiology and management at Johns Hopkins University in Baltimore, wrote an editorial accompanying the findings.

“As with all Phase 2 trials, the results need to be interpreted with caution until the Phase 3 results are published,” he writes. “But you still need to be careful after completing the Phase 3 exam and after getting your license.”

For more information

For more information on the COVID-19 vaccine, Centers for Disease Control and Prevention..

Source: Lancet infection, News Release, November 17, 2020

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