Description: What is Guillain-Barré Syndrome in some Covid-19 patients?

So far, 24 cases of Guillain-Barré syndrome have been added to the study of Mumbai physicians. (Express photo for expression)

In rare complications, some patients were infected COVID-19 It is known to be suffering from Guillain-Barré Syndrome (GBS). In India, such cases have been reported since August.

A group of Mumbai neurologists are currently mapping these cases and their symptoms. So far, 24 cases have been added to the study.

What is Guillain-Barré Syndrome?

This is a very rare autoimmune disease.The immune system is trying to kill Coronavirus, Accidentally begins to attack the peripheral nervous system. The peripheral nervous system is a network of nerves that connects the brain and spinal cord to different parts of the body. Attacking them can affect the functioning of the limbs.

The first symptom of the syndrome is a sensation of itching and itching of the skin, followed by weakness, pain, and numbness. Symptoms may first appear on the feet and hands. After that, one begins to experience loss of reflexes and paralysis. This may be temporary, but it can last for 6-12 months or more. With 1-year-old Covid-19, it is still difficult to assess the nature of persistent GBS in such cases.

GBS is caused by a bacterial or viral infection.In the past, patients with Middle East respiratory syndrome showed GBS symptoms as well as infected patients. Zika, HIV, herpesvirus, Campylobacter jejuni.

Connection with Covid-19

Covid-19 is known to affect digestive, cardiac and renal function. It is also known that some patients are prone to neurological problems when infected with the virus. When the virus attacks the parts of the brain that form the central nervous system, it can cause memory fog, anxiety, headaches, and depression.

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In all of these cases, the virus attacks organs or tissues and directly causes complications. However, in some cases it can have indirect consequences. It can provoke an immune response that is so strong that the body’s peripheral nervous system can be attacked. “It’s paradoxical. We all want a good immune system. But if the immune system is overactive, it can be harmful to the body. Global in Parel, Mumbai. Dr. Pankaji Agrawar, who heads the hospital’s movement disorder clinic, said:

June, The New England The Journal of Medicine has published an article detailing the cases of five patients suffering from the syndrome after being infected with the Sars-CoV-2 virus in three Italian hospitals. The initial symptoms were weakness in the lower limbs and a stinging sensation in the skin.

There is an interval of 5-10 days between the onset of GBS symptoms and Covid-19 infection, but some doctors say it can take weeks after Covid-19 infection to develop GBS. I will.

Last month, the British Medical Journal published a similar case from Japan in which a 54-year-old woman developed numbness and weakness and required two weeks of hospitalization. As a result of the test, she had pneumonia in her chest and the Covid-19 report was positive.

There is some consensus in various studies. Symptoms of GBS appear days after Covid-19 infection. Some patients who had recovered or were about to recover developed the condition, and most recovered.

Study in india

Multiple physician studies and registrations are underway in Mumbai and will be completed in three weeks. The study, led by Principal Investigator Dr. Megadam, a neurologist at Powai’s LH Hiranandani Hospital, collects case studies of GBS Covid-19 patients and maps their symptoms. Some neurologists in Mumbai are some of them. “GBS can leave permanent neurological damage. Most recover completely, but paralysis of the limbs and weakness of the body can occur for extended periods of time,” says Agrawal.

Agrawal adds that he saw the syndrome not only in adults but also in children. Most recovered from Covid-19, went home, and returned with GBS a few weeks later.

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Intravenous immunoglobulin (IVIG) and sometimes plasma therapy can help recover GBS patients. Some patients develop serious complications and may require intensive care or mechanical ventilation support.

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Studies show that patients need to be hospitalized for several weeks. Dr. Kedar Truska, director of critical care at Wokhart Hospital in Mumbai Central, said his condition could worsen if the patient was not treated. “The worst consequences can be respiratory failure, weakness and effects on gait and limb movements. Patients cannot be treated at home and are hospitalized and immunoglobulin or plasma. “I need it,” said Toraskar.

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