Oxford, England — The latest data from human clinical trialsThe vaccine being developed by Oxford University and AstraZeneca, the UK pharmaceutical giant, is safe and, most importantly, works well with the most vulnerable set of patients.
Peer-reviewed evidence published in The Lancet Medical Journal on ThursdayNot only does it provoke the strong immune response they wanted, but it also packs a strong punch into where it is most needed: the elderly.
Ongoing trials have shown that the vaccine is actually more tolerated in older people than in younger people.
In an analysis released Thursday, outside researchers scrutinized Oxford’s Phase II trials in 560 adults, including 240 people over the age of 70. This group is known to have a very high risk of serious illness and death from the coronavirus. Patients are most likely to fill an overstretched ICU ward and are designated to receive the vaccine first.
“The strong antibodies and T-cell responses we see in older people in our study are encouraging,” said Dr. Mahesi Ramasamy, co-author of the Lancet study at Oxford University. “I hope this means that our vaccine will help protect some of the most vulnerable people in society, but further research is needed before we can be convinced.”
Good news announced last weekAnd Further testing of their vaccines is underway and they will soon apply for an emergency license from the US government, but these vaccines use a similar approach, which has boosted Oxford’s vaccines. All three vaccines focus on the new coronavirus spike protein. This is the part that attaches to human cells and causes infection.
The Oxford team uses different biochemical processes, but the goals are the same. All three vaccines are intended to trick the body into initiating an immune response that prevents it from adhering to cells when this particular coronavirus is attacked.
It’s not yet entirely clear how long the immune response will last, but researchers are increasingly optimistic that the vaccine will remain effective for up to a year, if not more, after the recommended dose.
The Oxford team are “satisfied” with the results on Thursday, although the trials have not yet proven effective, but as Pfizer and Moderna announced, they are unique Phase 3 trials to speed them up. With others in the coming weeks who said they want to have the data.
Professor Andrew Pollard, a senior researcher at the Oxford Vaccine Team, said the news was encouraging, but said he was “not in a hurry.”
He said Oxford and AstraZeneca were “not competing with other developers. What we’re trying to do is make sure we have very high quality data … when we’re ready, it’s It’s time to provide interim results. “
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