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A network of 13 countries is conducting clinical trials of Africa’s largest COVID-19 treatment




Before entering Mpilo Hospita in Zimbabwe in April 2020, women check their body temperature.

KB Mpofu / ILO

Why global citizens should care

Due to systemic problems, coupled with the effects of the COVID-19 pandemic, millions of vulnerable Africans do not have access to quality medical care, reducing their quality of life and their ability to escape extreme poverty. I am. We need to take action to give everyone access to the quality medical care and tools they need to fight COVID-19, no matter where they live.Take action and participate in the exercise here..

Africa’s largest clinical trial of potential COVID-19 treatment in progress With the participation of a team of researchers from 13 African countries and around the world. The study was conducted after seeking a coronavirus response tailored to Africa’s unique healthcare. Task..

The study identified early-use treatments for mild to moderate cases of COVID-19, and a surge in hospitalizations that could overwhelm the continent’s already fragile, underfunded, and overburdened healthcare systems. The purpose is to prevent.

AnticovThe research called “” includes the Institute of Tropical Medicine Antwerp and international research institutes. Will be carried It has appeared on 19 sites in 13 countries and is led by African doctors.

“A large-scale clinical trial of COVID-19 in Africa is needed to answer research questions specific to the African situation,” said Dr. John Nkengason, director of the Centers for Disease Control and Prevention in Africa. Said Parent.

He added: “African countries have responded impressively to COVID-19 and now is the time to prepare for the future wave of the disease. It helps to answer one of our most pressing questions. Masu: In a limited intensive care facility in Africa-can we treat people with COVID-19 faster and prevent our hospitals from being overwhelmed? “

This trial is an open-label, randomized, controlled, adaptive platform trial, the first pioneered clinical trial method for anticancer drugs that allows simultaneous trials of various treatments. Test the effectiveness of the treatment 2,000-3,000 mild to moderate patients in Burkina Faso, Cameroon, Cote d’Ivoire, Democratic Republic of the Congo, Equatorial Guinea, Ethiopia, Ghana, Guinea, Kenya, Mali, Mozambique, Sudan and Uganda.

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The idea is to identify treatments that can prevent the coronavirus from progressing to serious disease and limit infection.Scientists testing adaptive platforms You will be able to make quick decisions Includes adding, continuing, or stopping treatment sections based on continuous analysis of results.

“The Institute for Tropical Medicine in Antwerp, Belgium has been working closely with our Ethiopian partners for many years.” Said Johan Van Griensven of the Institute of Tropical Medicine in Antwerp

“We can work with more than 10 other African countries to investigate whether patients with mildly ill COVID-19 who have been treated early are experiencing less serious complications.” He added. “In African countries, few hospitals have sufficient staff and intensive care units, so this strategy is necessary to avoid straining vulnerable healthcare systems.”

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Parents Report The trial will begin testing the HIV antiretroviral drug combination lopinavir-ritonavir and the malaria drug hydroxychloroquine. It remains the standard treatment for COVID-19 in many African countries today.

“It is encouraging to see so many African countries working together to get the coveted answer about the needs of our unique COVID-19 patients.” Said Dr. Borna Nyaoke-Anoke, Senior Clinical Project Manager for the Neglected Disease Drugs Initiative (DNDi), which also sponsors clinical trials in the Democratic Republic of the Congo, Kenya and Sudan.

She added: “Africa has largely avoided the massive deaths seen in other countries, but with the blockade and the opening of borders, preparations are needed. As a clinician, we can offer the best options for people with COVID-19. So, here in Africa there is a need for research to inform policy, testing and treatment strategies. “

Launched by seven global partners in April, ACT-Accelerator is a unique coalition aimed at accelerating the global commitment to the COVID-19 pandemic. Its members work together to develop tests, treatments, and vaccines as quickly as possible while strengthening the world’s most vulnerable healthcare systems.

However, the organization is in desperate need of financial support from governments around the world.You can participate in calling on world leaders to fund ACT-Accelerator by taking action here..

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