Health
Gout drug tested as a coronavirus treatment in a large UK trial
Ann Anti-inflammatory drug Widely used to treat gout and other symptoms are the latest treatments added to large-scale trials in the United Kingdom. Coronavirus.
Researchers Leading Random Assessment of COVID-19 Therapy (recovery) According to the study, colchicine will be tested in hospitalized coronavirus patients.
“Colchicine is a very well-understood, inexpensive and widely available drug that makes it an attractive drug to evaluate in the RECOVERY trial,” said Professor Peter Horby, co-principal researcher in the RECOVERY trial. In a news release. “If that works, even the poorest countries will have another COVID-19 treatment that is readily available around the world.”
According to Reuters, Colchicine costs about $ 124 for 30 capsules.
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In addition to gout, the drug has already been approved for the treatment of inflammatory conditions such as pericarditis. According to the study organizers, inflammation is a factor in severe COVID-19 cases and can lead to lung damage, ventilator needs, and even death.
“Inflammation plays a major role in COVID-19 and has already shown that treatment with one anti-inflammatory drug, dexamethasone, can reduce mortality in the most severe COVID-19 patients,” said RECOVERY co-leader. Said Professor Martin Landray. , Said in a news release. “Colchicine is very widely used in the treatment of other inflammatory conditions such as gout and pericarditis. Whether including colchicine in the RECOVERY trial will help address the worst outcomes of COVID-19. You can check. “
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The drug is initially given to up to 2,500 patients enrolled in the study at a dose of 1,000 micrograms, followed by 500 micrograms every 12 hours for up to 10 days. According to a news release, the study will assess mortality after 28 days and its impact on hospitalization and ventilation needs.
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The drug joins several other treatments being investigated in recovery trials, including tocilizumab, convalescent plasma, regeneron, and aspirin. Researchers say that azithromycin registration has already ended.
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