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Team Behind Oxford Covid Jab Begins Final Stage of Malaria Vaccine Trial | World News


The successful Coronavirus vaccine team is about to enter the final stages of a human clinical trial in search of malaria vaccination.

Professor Adrian Hill, director of the Jenner Institute, said that 4,800 children in Africa will be tested for the malaria vaccine next year after promising results from early trials.

In an interview with The Times, Hill said malaria was a public health emergency.

More than 400,000 people die from the disease each year, and children under the age of five die every two minutes in Africa.

“In Africa this year, far more people will die of malaria than they will die of Covid. I don’t mean twice, maybe ten times,” Hill said. The vaccine “will be available in very large quantities, it works pretty well, and it will be very cheap.”

If the final human trial is successful, the vaccine could be used by 2024, he said. Despite a century of research, this is seen as a potential breakthrough given the lack of a fully licensed vaccine against malaria. GSK is the only pharmaceutical company approached, but its product is only 30% effective.

The institute’s coronavirus vaccine is also aimed at making it inexpensive and large-scale available in developing countries. Jab exams will begin next year in Burkina Faso, Kenya, Tanzania and Mali. Early phase II trials looked good so far, and Oxford worked with the Indian Serum Institute to produce the dose.

This is because the Oxford / AstraZeneca coronavirus vaccine is awaiting regulatory approval for use in the United Kingdom. Oxford researchers have announced that most volunteers have a 62% efficacy of the vaccine, compared to the 90% or more recorded for vaccines produced by Pfizer and Moderna.

However, the researchers said that as a result of manufacturing problems, a subset of volunteers were mistakenly given a low dose of the vaccine and were given that low dose. Produced higher efficacy About 90%. They did not explain the anomaly.

“The Covid-19 pandemic shows how much the world is at risk of infectious diseases,” Azlagani, a professor of infectious disease epidemiology at Imperial College London, told the Times. “Vaccines that are very effective against malaria can have a significant impact on reducing this risk.”


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