Dear Doctor.. cockroach •• You seem to be promoting statins. How about statins for the elderly? Recent studies from 2017 It was peer reviewed and seemed to be well done “There is no benefit to pravastatin for primary prophylaxis in the elderly with moderate hyperlipidemia and hypertension, and there is a significant increase in all-cause mortality from pravastatin in adults 75 years and older. No direction was observed. ”Is this an important result? — RBR
Answer • Statins are recommended for people at high risk of heart disease and stroke, but only after a comprehensive study of all risk factors. In many cases, you can reduce your risk by changing your lifestyle, especially your diet and exercise. In some cases, the risk can be reduced to the point where statins are no longer needed.
Until quite recently, older people were not the subject of much research. On the other hand, we don’t want to treat people without good reason to expect the benefits to outweigh the risks. Older people, on the other hand, are at increased risk of developing vascular disease and its complications.
The 2017 study you cite has been overturned by more recent studies. In a 2019 review of all available trials, elderly people with known cardiovascular disease (arterial obstruction) have significant benefits in reducing the need for procedures such as heart attack, stroke, and bypass surgery. Was shown. A 2020 study of veterans with an average age of 81 years without heart obstruction showed that starting statins in this older group reduced overall mortality by about 25%. Another way to look at it is that about 23 people die annually from cardiovascular causes of statins, and 26 per 1,000 people die annually from cardiovascular causes if statins are not taken. This study was not a clinical trial. It just saw if one doctor put them in statins at an older age.
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