Health
COVID-19 drug that provides hope, Mornupyravir
“These properties make MK-4482 / EIDD / 2801 a strong candidate for the pharmacological regulation of Covid-19,” he added.
In a study published in Nature Microbiology, Plemper’s team reused MK-4482 / EIDD-2801 for SARS-CoV-2 and used a ferret model to test the effectiveness of drugs that block the spread of the virus. Did.
“We consider ferrets to be a related model of infection because they easily spread SARS-CoV-2, but most often develop severe illnesses that closely resemble SARS-CoV-2, which prevails in young adults. “No,” said postdoctoral fellow Robert Cox. Co-author of research with the Plemper group.
Researchers infected ferrets with SARS-CoV-2 and began treatment with MK-4482 / EIDD-2801 when animals began releasing the virus through their noses.
“When infected animals were treated in the same cage with untreated contact ferrets, none of the contacts were infected,” said Josef Wolf, a PhD student in the Plemper lab and co-lead author of the study. By comparison, all contacts of placebo-treated source ferrets were infected.
Reportedly, the Scientific and Industrial Research Council (CSIR) will soon make a decision on conducting human clinical trials of the drug.
In developments related to the Covid 19 vaccine, UK drug regulators dismissed safety concerns about Pfizer and the BioNTech vaccine after reports revealed that four people had Bell’s palsy in a U.S. trial. It was.
Usually in a temporary state, the nerves are not functioning properly and the muscles on one side of the face hang down.
The Daily Mail reported that four cases were found in a group of 21,720 people vaccinated with Pfizer in a study in the United States, compared with none among 21,728 people vaccinated with placebo.
However, this incidence is the same as the frequency expected to occur in a random population. In the UK, there are about 20-30 cases per 100,000 people annually.
The US Food and Drug Administration said in its report: “The four cases in the vaccine group do not exceed the expected frequency in the general population.”
The Daily Mail says that this is almost certainly random that all people who developed the condition happened to belong to a vaccine group, and regardless of the vaccine, the same number of people have it in a group of that size. I reported that it meant that there was a possibility.
MHRA, a UK counterpart, said: “The general safety profile of this vaccine is similar to other types of routinely used vaccines. Vaccine supply in the UK unless expected safety, quality and efficacy criteria are met. Is not allowed. “”
According to the report, the Pfizer / BioNTech vaccine, which has proven safe in clinical trials, is currently being offered to the general public in the United Kingdom, the first country to jab citizens.
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