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Forgetting the beginning of the story may be a sign of dementia




According to experts, forgetting the beginning of the story may be an early sign of dementia.

Scientists have found that delayed narrative recall is associated with high levels of a protein in the brain known as amyloid beta, an indicator of Alzheimer’s disease.

The team said the findings published in the Journal of Neuropsychology could be “a cheap and accurate way to identify dementia in people who are otherwise asymptomatic.”

Dr. Davide Bruno, Department of Psychology, Liverpool John Moores University (LJMU), was the first author of the study and said: “The presence of amyloid plaques in the brain is hypothesized to initiate neurodegeneration in Alzheimer’s disease.

“I don’t know the exact reason, but if you forget what you learned first, Alzheimer’s disease may be established.

“I think it’s related to the preservation of information about the order of events. It’s a fundamental feature of memory, and its loss is somewhat similar to a coal mine canary.”

LJMU and a team of scientists at the University of Wisconsin-Madison in the United States analyzed data from the Wisconsin Registry for Alzheimer’s Prevention, an ongoing family history study of Alzheimer’s disease.

They investigated the memory abilities of 653 people to see if they were easier to remember the first part of the story than in the middle of the story.

“I knew that people who forgot the first thing on the list were at increased risk of dementia, so I wanted to see if it was the same for other types of memory,” said Dr. Bruno. ..

Next, researchers examined 223 subsamples and how well they remember the beginnings of two stories where evidence of amyloid plaques in the brain is part of a common neuropsychological test. I checked if it was.

The authors found that forgetting the beginning of the story was associated with high levels of amyloid in the brain.

Dr. Bruno said: “Not all memories are the same.

“Storyes benefit from a consistent structure, so it can be easier to remember a story than to remember an item in a list.

“Therefore, I wasn’t sure if the order in which I learned the information would affect my memory when I remembered the story.

“I knew it would happen.”


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