Health
BAT Advances COVID-19 Vaccine Candidates to Phase I Clinical Trials
The COVID-19 vaccine candidate (KBP-COVID-19; NCT04473690) is one of many potential vaccines that have advanced beyond preclinical trials. The study is designed to enroll a total of 180 healthy volunteers, divided into two age cohorts, 18-49 years and 50-70 years. Each group is then subdivided into low-dose and high-dose treatment groups (N-45), randomized 2: 1 and low-dose (15 μg KBP-COVID-19 vaccine + 0.5 mg adjuvant) or placebo, or High dose (45 μg KBP-COVID-19 vaccine + 0.5 mg adjuvant) or placebo. The results of this study are expected in mid-2021, and if positive, will allow continued progress to Phase 2 studies, subject to regulatory approval.
Candidate vaccines were developed using KBP’s innovative fast-growing plant-based technology. This unique approach has many advantages, including the rapid production of the active ingredient of the vaccine in about 6 weeks compared to the months using traditional methods. Candidate vaccines can also be stable at room temperature, which can be of great benefit to healthcare systems and public health networks around the world. If successful, the rate of production of the active ingredient may reduce the time between identifying a new virus or strain and developing the vaccine and deploying it to those in need.
KBP is enrolling in a Phase I clinical trial of a 4-valent (4 strain) influenza vaccine candidate (KBP-V001; NCT04439695) using the same Nicotiana Bensamiana plant-based technology platform, which has recently been completed. did.
The move to human trials with both COVID-19 and seasonal influenza vaccine candidates is an important milestone and reflects a great deal of effort to accelerate the development of new biological portfolios. It is a unique plant-based vaccine technology that acts as a fast and efficient host for the production of antigens for a variety of diseases, making this advance and urgent global need for safe and effective treatments. It is possible to correspond to. vaccine. “
BAT, Director of Scientific Research, Dr. David O’Reilly
“This is part of our ongoing commitment to innovation and science, which are the foundation of our business. As a company working to build ABetter Tomorrow, we are proud to be part of the global fight against this virus. Please contribute to the solution. “
As both vaccines reach these important milestones, the science and unique platform for tobacco plant-based vaccine development continues to gain momentum.
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What Are The Main Benefits Of Comparing Car Insurance Quotes Online
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