Health
A new study states that the COVID-19 virus can cause the blood-brain barrier
A new study by the University of Washington Health Sciences / UW Medicine argues that the COVID-19 virus may show patients cognitive effects such as brain fog and malaise.
Studies published in Nature Neuroscience show that SARS-CoV-2, the cause of COVID-19, can invade the brain. Through a mouse model, researchers have discovered that spike proteins, often depicted as the red arms of the virus, can cross the blood-brain barrier in mice. Spike proteins, often referred to as the S1 protein, determine where the virus can enter. Usually, the virus does the same thing as its binding protein, said William A. Banks, a professor of medicine at the University of Washington School of Medicine and lead author William A. Banks, a physician and researcher at the Puget Sound Veterans Medical System. “Binding proteins like S1 usually separate from the virus and cause inflammation, which themselves cause damage. S1 proteins are likely to release cytokines and inflammatory products into the brain. ..
“In the scientific world, the severe inflammation caused by COVID-19 infection is called a cytokine storm. When the immune system sees a virus and its proteins, it overreacts in an attempt to kill the invading virus. Left. Fog, fatigue, and other cognitive problems The bank and his team wanted to see this reaction to the HIV virus and see if the same thing was happening with SARS Cov-2.
According to the bank, the SARS-CoV2 S1 protein and the HIV-1 GP120 protein function similarly. They are glycoproteins-proteins that have a lot of sugar on them, a characteristic of proteins that bind to other receptors. Researchers have also discovered that both of these proteins act as the arms and hands of the virus by grabbing other receptors. Both cross the blood-brain barrier, and like gp120, S1 can be toxic to brain tissue.
Fifteen people in the lab started experimenting with the S1 protein in April. They included Jacob Labor, a longtime collaborator who is a professor of behavioral neuroscience, neurology, and radiology, and his team at Oregon Health & Science University. This study was able to explain many complications from COVID-19.
“The additional explanation is that the virus enters the respiratory center of the brain, where it also causes problems,” Banks said.
For those who downplay the virus, Banks said, “I don’t want to mess with this virus. Many of the effects of the COVID virus can be highlighted, perpetuated, or caused by a virus that has invaded the brain. , Their effects may be sustained. ” a month of Sundays”
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