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A new antibody therapy that may stimulate immunity to COVID-19 will be launched on a trial basis

A new antibody therapy that may stimulate immunity to COVID-19 will be launched on a trial basis

 


As the UK continues to fight new cases of COVID-19 among the more contagious strains of the virus, London scientists are testing antibody treatments aimed at protecting against COVID-19.

Researcher at University College London (UCLH) Presentation They administered the first dose of antibody treatment candidates to patients on Christmas day. A large study led by UCLH researchers recruited a total of 10 volunteer patients, who received one dose per person.

Pharmaceutical company AstraZeneca — its potential COVID-19 vaccine The following vaccines have been approved For emergency use — We have also developed a long-term active antibody (LAAB) known as AZD7442. This may help the human immune system stimulate protection against COVID-19 in people exposed to the virus.


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The study is led by Catherine Houlihan, a UCLH virologist who is responsible for the UCL infection and immunity department.

Antibodies, or proteins produced by the immune response, seek out foreign invaders, such as viruses, in the body and eliminate them. The general theory of antibody-based treatment is that if the body can preemptively have antibodies that recognize the virus, it will respond better to infection.

LAAB is composed of monoclonal antibodies that are artificially created and administered to strengthen the immune system.

“We know that this combination of antibodies can neutralize the virus, so we hope that this treatment by injection will provide immediate protection against the development of Covid-19 in exposed people. “Vaccine,” said Furihan.

The US government has helped AstraZeneca fund LAAB in the hope that treatment will work if clinical data can prove effective. Complementary For vaccines.

It may also be useful for people who are particularly susceptible to severe COVID-19 infections and may act as a vaccine alternative if needed.

“We are looking for older people and caregivers who have cancer, HIV, or other conditions that can affect the ability of the immune system to respond to vaccines,” said a UCLH infectious disease expert. Nicky Longley said. Said. “We want to reassure people who may not be vaccinated that we can provide the same preventative alternatives.”

LAAB is designed to be given once, as opposed to two doses of the vaccine created by Pfizer and Moderna.

It is designed to last 6 to 12 months after administration.


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