Health
Brain Imaging Predicts Post-Injury PTSD and Discovers Research-Health
Post-traumatic stress disorder (PTSD) is a complex mental disorder caused by physical and / or psychological trauma. How symptoms such as anxiety, depression, and cognitive impairment occur is not fully understood and unpredictable. Researchers currently using magnetic resonance imaging (MRI) have discovered potential brain biomarkers for PTSD in people with traumatic brain injury (TBI).
This study is published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier.
“The relationship between TBI and PTSD has received increasing attention in recent years because studies have shown a significant overlap of risk factors and symptoms,” said lead authors Murray Stein, MD, MPH, FRCPC, psychiatry and family medicine. And a prominent public professor states Health at the University of California, San Diego, San Diego, La Jolla, California, USA. “This study was able to use data from TRACK-TBI, a large longitudinal study of patients in the emergency department with a TBI serious enough to justify a CT (Computed Tomography) scan. It was. “
Researchers followed more than 400 such TBI patients and evaluated PTSD 3 and 6 months after brain injury. At 3 months, 77 participants (18%) may have had PTSD. In 6 months, 70 participants or 16% participated. All subjects underwent brain imaging after the injury.
“MRI studies performed within two weeks of injury were used to measure the amount of important structures in the brain that may be involved in PTSD,” said Dr. Stein. “Some amounts of these structures have been found to predict PTSD 3 months after injury.”
Specifically, smaller volumes of the cingulate cortex, upper prefrontal cortex, and areas of the brain called islands predicted PTSD at 3 months. These areas are associated with alertness, attention, and emotional regulation. Structural images did not predict PTSD in 6 months.
Findings are one with previous studies showing smaller volumes in some of these brain regions of people with PTSD and studies suggesting that reduced cortical volume may be a risk factor for developing PTSD. I am doing it. Together, the findings suggest that “brain reserve”, or higher cortical volume, may provide some resilience to PTSD.
Biomarkers of differences in brain volume are not yet robust enough to provide clinical guidance, but Dr. Stein said: Health problems such as PTSD. “
Dr. Cameron Carter, MD, Editor of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging said of the study: In the future, brain imaging is also aimed at predicting that humans are at high risk and may benefit from targeted interventions to mitigate the clinical impact of traumatic events. Lay the foundation for your research. ”
(This story is published from the news agency feed without changing the text.)
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