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New Covid variant associated with increased viral load in respiratory samples | Coronavirus

New Covid variant associated with increased viral load in respiratory samples | Coronavirus

 


The hypothesis that the rapidly prevailing British variant of the Covid-19 virus has the benefit of infection is supported by analysis suggesting that it is associated with a higher load of the virus in respiratory samples. I have.

A variant named B117 was discovered during an investigation into why cases of coronavirus in Kent continued to increase during the November blockade. Scientists have found that while older variants are declining, they continue to spread during restrictions.

Some of the lighthouse laboratories established in April to enhance Covid-19 testing capabilities, such as in London and Manchester, have respiratory organs when the Covid-19 Genomics UK Consortium warned about B117 and its infection. I was beginning to see evidence of new mutations in the sample. advantage.

Dr. Michael Kidd of the PHE Institute for Public Health in Birmingham and his team analyzed a total of 641 samples based on tests from symptomatological patients and found evidence of B117 among other variants. Approximately 35% of patients infected with B117 had higher levels of virus in their samples compared to 10% of patients without mutants, they said. Studies that have not yet been peer reviewed..

“Patients with this variant appear to have a high viral load. What is clear is that they are more susceptible to infection by others,” said Kidd, who said the data were preliminary and gathered more evidence. I warned that I needed to. Before drawing a firm conclusion.

Scientists say they have High reliability that B117 has transmission advantages – In a modeling study by researchers at the London School of Economics and Tropical Medicine, 56% more contagious than previous variants..

Numerous factors can explain why it is more contagious. The more infectious the mutant, the less viral particles the host needs to pass the pathogen. The virus can also replicate faster in the respiratory tract, infect people longer, and make them more susceptible to infection.

“Exactly how [the variant] Reaching high viral load is another big issue, “Kid said, adding that laboratory-based confirmation is needed to understand the biological basis of the benefits of transmission.

“We need other evidence, like a piece of a jigsaw puzzle. The importance of this study, which needs to be preliminary and repeated, is a kind of ground-based explanation of why this virus has the ability to spread more easily. I think it will provide because the patient is more infectious. “

Initial data British variants suggest that they do not make people sick or increase the likelihood of reinfection or death. However, high infection rates without strict control can still lead to high mortality rates.

• This article was revised on December 30, 2020. As mentioned in previous versions, higher viral load was found in respiratory samples rather than blood samples.

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