Connect with us


Update 1-COVID-19 Plasma study shows no benefit to critically ill patients


(Add background and call for blood donation for ongoing testing)

London, January 11 (Reuters)-An international study testing convalescent plasma in the case of moderate and severe COVID-19 finds that plasma is useless and then requires intensive care in critically ill patients Has stopped registering, the test researcher said on Monday.

The REMAP-CAP study leader’s decision was the first analysis of more than 900 critical care unit participants in the intensive care unit, treated with a product that is antibody-rich plasma from people who have recovered from a pandemic disease. It was done after it was shown that it was not done. Improve the result.

“There was no evidence of harm associated with convalescent plasma administration.” (And) the study continues to recruit inpatient COVID-19 patients with moderate illness but no intensive care. The scientist leading the test said in a statement.

“It is biologically plausible that patients who do not produce antibodies at the time of convalescent plasma therapy or who have excess virus may benefit more than others. Our additional analysis will explore this, “said Manushan Kahari, a clinician and professor of critical care medicine at Guys and St. Thomas Hospitals in the United Kingdom, who co-leads the trial. It was.

He added that the initial analysis did not assess the effects of plasma on less severe inpatients. This is “still a very important issue,” he said, and will continue to be investigated in ongoing trials.

The underlying hypothesis for using convalescent plasma as a potential treatment for COVID-19 patients is that the antibodies contained in convalescent plasma neutralize the virus, block virus replication, and stop tissue damage. There is a possibility of causing it.

A small study of convalescent plasma in patients with COVID-19 in India and Argentina also showed no apparent benefit in severe or severe patients with the disease.

Analysis leading to the suspension of REMAP-CAP in critical care enrollment showed a very low probability (2.2%) of reduced mortality and reduced number of days patients need intensive care. I did.

“It is not yet known why convalescent plasma does not appear to improve outcomes in critically ill COVID-19 patients admitted to the ICU. However, it is because convalescent plasma is too advanced for lung damage. It may be because we can’t make a difference, “said Alexis Turgeon, an emergency physician and professor at Laval University in Canada, who is also working on the exam.

However, scientists and doctors called for continuing convalescent plasma testing and continuing to donate blood in the hope that recovered COVID-19 patients would help others.

“Antibodies work by stopping the virus, not by treating the symptoms,” said Gale Mifflin, a medical expert in the blood and transplant department of the United Kingdom National Health Service. “New evidence from international studies may prove that pre-intensive care use is more effective.”

REMAP-CAP is an international clinical trial investigating various potential treatments for COVID-19. We are already recruiting 4,100 COVID-19 patients for convalescent plasma trials in more than 290 clinical centers in Europe, the Americas, Asia, Africa and Australasia.

Treatment of severely ill COVID-19 patients with Roche’s Actemra or Sanofi’s Kebuzara arthritis drug significantly improves survival and the patient’s time to require intensive care, according to a study separate from REMAP-CAP It has been shortened. (Report by Kate Kelland, edited by Nick Macfie)


What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

Pictures Credit


to request, modification Contact us at Here or [email protected]