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The first Pfizer COVID vaccine shot reduces the risk of infection by 50%: Study

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Preliminary data from the Israeli mass vaccination program suggest that the Pfizer-BioNtech vaccine reduces the risk of infection by about 50% 14 days after the first two doses.

Sharon Alroy Price, chief of the Israeli Ministry of Health, told Channel 12 News of the country that the conclusions are based on the results of hundreds of thousands of COVID-19 tests.

Israel is currently the world leader in vaccination, immunizing nearly one-fifth of its population.

About 2 million people vaccination In a small country in the Middle East, more than 5 million Israelis will be shot by March if the plan developed by the Ministry of Health goes well.

Alroy-Preis said that about one-fifth of more than 1,000 COVID-19 patients in the country with serious illness have already received the first dose of the Pfizer-BioNtech vaccine, preventing it during administration. He emphasized the importance of taking measures.

“17% of today’s new serious cases, or 180, are after the first dose,” Alroy-Preis told reporters.

Pfizer-BioNtech vaccine It has been shown to reduce the risk of individuals developing COVID-19 by 95%. However, this level of protection, and long-term immunity, is only reached more than a week after the second dose. This second dose is to be given 21 days after the first dose.

Published in BMJ Examination of the results of Phase III clinical trials has previously shown that the vaccine may provide some early protection, but this only begins about 12 days after the first dose.

The· BMJ Studies have shown that the vaccine was 52% effective between the first and second doses when given at 21-day intervals.

The above estimates are slightly different from those released by two of Israel’s four major health maintenance organizations (HMOs) on Tuesday, based on data from 400,000 patients in each region.

Clarit, the largest HMO, reported that the risk of infection was reduced by only 33% 14 days after the first shot, but McCabi HMO said this figure was about 60%. The reason for the discrepancy between these numbers is not clear at this time.

Data from Israel may provide the best indicator of vaccine efficacy after the first dose. PfizerA smaller number (approximately 40,000) participated in our own Phase III study.

In England Authorities have decided to administer the Pfizer vaccine every 12 weeks to combat the rapid increase in infections.The National Institute for Genomic Research and Immunization (JCVI) stated that the short-term efficacy of shots increased to 89% between 15 and 21 days after the first dose.

However, JCVI said protection from the first dose “decreased in the medium term and a second dose is still needed to provide more durable protection.”

Israeli Pfizer COVID-19 Vaccine
On January 12, 2021, health care workers will prepare for COVID-19 vaccination at the Clarit Health Service in the Palestinian district of Beit Hanina in East Jerusalem, where Israel has been annexed.
AHMADGHARABLI / AFP via Getty Images

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