Thursday, January 14, 2021 (HealthDay News)-Patients with type 2 diabetes who have been on a low-carbohydrate diet (LCD) for 6 months have diabetic remission, according to a review published online on January 13. The rate can be high. BMJ..
Joshua Z. Goldenberg, Ph.D., College Station, Texas A & M University. We conducted a systematic review and meta-analysis to investigate the efficacy and safety of LCDs and very LCDs (VLCDs) in patients with type 2 diabetes. Data were included from 23 trials with 1,357 participants.
Researchers found that LCD achieved a higher rate of diabetes remission (defined as hemoglobin A1c) in 6 months compared to a control diet. [HbA1c] <6.5 percent; 57 to 31 percent. Risk difference, 0.32). A smaller, non-significant effect size was seen when the definition of HbA1c <6.5% remission was used without medication. Data on remission at 12 months were sparse, ranging from small effects to a slight increase in the risk of diabetes. There were significant clinically significant improvements in weight loss, triglycerides, and insulin sensitivity at 6 months, but decreased at 12 months. VLCDs seemed to be less effective than less restrictive LCDs. This effect was explained by dietary adherence. There was no significant difference in quality of life at 6 months. However, clinically significant but not statistically significant deterioration was seen at 12 months.
“Clinicians may consider short-term LCDs for the management of type 2 diabetes, while actively monitoring and adjusting antidiabetic drugs as needed,” the author writes.
One author revealed a financial relationship with Texas A & M AgriLife Research.
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