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University of Michigan Participating in Trials Showing Benefits of COVID-19 Anticoagulant Treatment




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Three clinical trial platforms across five continents in more than 300 hospitals have collaborated since May last year to treat adults hospitalized for non-critical COVID-19 disease, all of heparin (anticoagulant) We are urgently testing if there is a greater benefit to the dose. To low doses usually given to prevent blood clots in inpatients.

Based on the interim results of more than 1,300 moderately admitted patients, the findings show that not only are all doses of anticoagulants safe, but they are better than the doses normally given to prevent blood clots in inpatients. I showed that. Moderate patients are those who do not participate in the ICU and do not receive ventilator or other organ support at the time of study enrollment. Investigators are currently working as quickly as possible to make the full results of the study available so that clinicians can make informed decisions about the treatment of patients with COVID-19.

The results of these trials, reported Friday, found a group that routine use of full-dose anticoagulant when initiated in the ICU of critically ill COVID-19 patients appears to be non-beneficial and harmful. It is a complement to.

Early in the pandemic, doctors around the world observed an increased incidence of blood clots and inflammation in COVID-19 patients. It affected multiple organs and caused complications such as lung failure, heart attack and stroke. It was unclear at the time whether increasing the dose of anticoagulants routinely given to inpatients was safe and effective.

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