US regulators have approved the first long-acting drug combo for HIV that can replace the daily tablets currently used to control the transmission of the AIDS virus.
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FDA Approves First Long-Acting HIV Drug Combo, Monthly Shots | Home + Life + Health
This month’s approval of a two-shot combo called Cabenuva is expected to make it easier for people to get on track with HIV drugs and protect their privacy. This is a major change from a short time ago when patients had to take multiple tablets several times a day and carefully adjust their meal timing.
“It will improve quality of life,” said Dr. Stephen Dikes, an HIV expert at the University of California, San Francisco, who has nothing to do with pharmaceutical companies. “People don’t want daily reminders of being infected with HIV.”
Cabenuva is a combination of rilpivirine, marketed as Edurant by Johnson & Johnson’s Janssen unit, and cabotegravir, a new drug from ViiV Healthcare. They are packaged together and given as separate shots once a month. Dosing every two months has also been tested.
The US Food and Drug Administration has approved Kavenuba for use in adults who are well controlled by traditional HIV drugs and who do not show signs of viral resistance to the two Kavenuba drugs.
Authorities also approved a pill version of Cabotegravir to be taken with rilpivarin for a month before switching to shots to ensure that the drug was well tolerated.
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