Health
How Does the Comirnaty Vaccine Work?
The first phase Covid-19 vaccine supply from Pfizer-BioNTech will arrive in Malaysia on February 26th. Below are some frequently asked questions about Pfizer-manufactured Comirnaty vaccines answered by the Institute for Medical Research.
Q: How does the Comirnaty vaccine react in the body?
A: The Comirnaty vaccine uses messenger ribonucleic acid (mRNA) vaccine technology. The mRNA vaccine is composed of gene sequences that protect the mRNA from enzymatic reactions in the body and ensure that the mRNA can invade specific immune cells such as dendritic cells and macrophages in the lymph nodes near the injection site. The mRNA vaccine produces a unique protein called the spike protein, which can stimulate the body’s immunity without causing disease. After the peplomer is produced, the mRNA vaccine is enzymatically destroyed. The mRNA sequence does not enter the nucleus and does not contain intracellular genetic DNA material. Peplomers produced by the mRNA vaccine promote the formation of specific antibodies against Covid-19 and may react in the event of future Covid-19 infections.
Q: Can Comirnaty vaccines change human DNA and genetics?
A: No. Comirnaty vaccines cannot alter human DNA or genetics because mRNA does not enter the nucleus of the cell and does not react with DNA.
Q: Can Comirnaty vaccines cause Covid-19?
A: No. The Comirnaty vaccine does not use the live SARS-CoV-2 virus. Therefore, it does not cause Covid-19.
Q: Who can get the Comirnaty vaccine?
A: Anyone over the age of 18 can be vaccinated.
Q: How many times do I need to get the Comirnaty vaccine?
A: All individuals should be vaccinated twice with a 21-day interval between the first and second doses.
Q: Who is not suitable for Comirnaty vaccination?
A: Not suitable for vaccination:
> Individuals with a history of serious allergies to certain foods, medications, or the environment that require hospital treatment.
> Individuals who have experienced severe allergies after the first dose of the vaccine.
> People who received a kidney transplant or an organ transplant such as a blood cell stem 3 months before vaccination.
> Individuals receiving cancer treatments such as chemotherapy, radiation therapy, and immunotherapy.
> HIV patients with white blood cell count CD4 <200 cells / mL.
> Pregnant women or those planning to become pregnant.
> People who have a fever due to a viral or bacterial infection.
> People who received monoclonal antibodies or plasma as treatment for Covid-19 3 months prior to vaccination.
> People with low platelet levels.
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