Health
Can mRNA cure illness?
Second, the FDA has not yet approved any of these treatments.
In addition, some early trials of mRNA therapy suffer from major obstacles on the road to market approval.
January, CureVac reported Disappointing result In clinical trials of the new mRNA-based drug Prostate cancer.. The company’s CV9014 drug did not increase the survival rate of men with metastatic prostate cancer or stop the progression of the disease, which is the two main goals of the study.
CureVac founder Ingmar Hoerr, PhD, called this finding a temporary setback, CV9014 was shown to be safe, and preclinical studies were combined with other immunotherapeutic agents known as checkpoint inhibitors. It suggests that it may prove to be effective if you do.These medicines like merk Keytruda, Bristol Myers Squibbs Opdivo, And Roche Tecentriq, CV9014 When the study began, it was not on the market.
“We are already planning to work with our partner Boehringer Ingelheim to begin clinical trials of mRNA in combination with checkpoint inhibitors.” Hoerr told the European publication Labiotech.
Both companies Alliance About another prospective mRNA vaccine for lung cancer.
But the CureVac recession, backed by Microsoft co-founder Bill Gates and German entrepreneur Dietmar Hopp, reminds us that mRNA faces significant therapeutic hurdles.
This is especially true when creating new treatments for thousands of different types of cancer, each with its own challenges.
Maurie Markman, MD, says mRNA therapy is promising. But he draws attention with the optimism produced by the Moderna and Pfizer COVID-19 vaccines.
“Cancer treatment is a different world than innovation to prevent cancer,” said Markman, president of medicine and science at the US Cancer Treatment Center.
“Unfortunately, we conclude with simple words such as RNA, DNA, vaccines, etc.” If we can treat a group of diseases, including viruses, and succeed in this area, we cannot take. Are you working on the same technology, the same strategy, and another illness? And the answer is: You absolutely have to look, but it’s problematic to assume that you’re looking at something comparable. “
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