Connect with us

Health

Heart damage seen in more than half of discharged COVID-19 patients

 


退院したCOVID-19患者の半数以上に見られる心臓の損傷European Heart Journal“width =” 800 “height =” 530 “/>

MRI scan of the injured heart. Blue means reduced blood flow and orange means good blood flow. In this figure, the lower part of the heart is shown in dark blue, which greatly reduces blood flow in the myocardium, and a black-and-white angiography that looks directly at the blood vessels shows the blood vessels that supply blood to this part of the heart. I am. It is blocked. The three color images are three different slices of the heart. The basal slice and the apex slice. credit: European Heart Journal

Approximately 50% of patients who are hospitalized with severe COVID-19 and have elevated levels of a protein called troponin have heart damage. Injuries were detected by magnetic resonance imaging (MRI) scans at least one month after discharge, according to new findings released today. European Heart Journal..

Inflammation includes inflammation Muscle (myocarditis), scarring or death of heart tissue (infarction), restriction For the heart (ischemia) and all three combinations.

148 studies Studies from six acute hospitals in London are the largest studies to date to investigate the recovery of patients with COVID-19 who have elevated troponin levels that may indicate heart problems.

Troponin is released into the blood when the heart muscle is damaged. Elevated levels can occur when arteries are occluded or the heart is inflamed. Many patients hospitalized with COVID-19 have elevated troponin levels at the stage of serious illness when the body initiates an exaggerated immune response to infection. Troponin levels were elevated in all patients in this study, after which an MRI scan of the heart was followed after discharge to understand the cause and extent of the injury.

Marianna Fontana, a professor of cardiology at University College London (UK), who led the study with Dr. Graham Cole, a cardiologist at Imperial College London, said: “Elevated troponin levels are associated with worse outcomes in COVID-19 patients. Patients with severe COVID-19 infections have pre-existing heart-related health issues such as diabetes, elevated blood pressure, and obesity. Often there are problems. However, during severe COVID-19 infections, the heart can also be directly affected. Although damage is difficult, MRI scans of the heart can identify different patterns. This may allow you to make a more accurate diagnosis and target your treatment more effectively. “

Researchers found COVID-19 patients discharged from six hospitals by June 2020: three NHS London Trusts (Royal Free London NHS Foundation Trust, Imperial College Healthcare NHS Trust, University College London Hospital NHS Foundation Trust) Was investigated. Patients with abnormal troponin levels were provided with an MRI scan of the heart after discharge and compared to patients from the control group of patients who did not have COVID-19, and patients from 40 healthy volunteers. I did.

“The recovering COVID-19 patients were very ill. All required hospitalization, all had elevated troponin, and one in three used a ventilator in the intensive care unit.” Professor Fontana said.

“We found evidence of a high rate of myocardial damage that could be seen on scans a month or two after discharge. Some of this may have been existing, but some MRI scans. Is new and probably caused by COVID- 19. Importantly, the patterns of damage to the heart vary, suggesting that the heart is at risk of different types of damage. The damage in progress was negligible, but the damage to the heart was not impaired in the heart’s pumping function and may not have been detected by other techniques. In the most serious cases. There is concern that this injury may increase the risk of future heart failure, but more work is needed to investigate this further.

The function of the left ventricle of the heart, the ventricle responsible for pumping oxygenated blood to all parts of the body, was normal in 89% of 148 patients, but myocardium in 80 patients (54%). Scaring or damage was seen. .. The pattern of tissue scarring or damage is ischemic heart disease, including inflammation, infarction or ischemia in 39 patients (26%), 32 patients (22%), or 9 patients (6%). Due to both. Twelve patients (8%) appeared to have ongoing cardiac inflammation.

Professor Fontana said: “Inflammation and scarring-related injuries to the heart are common in COVID-19 patients with elevated troponin discharged from the hospital, but to a limited extent and have little effect on heart function.

“These discoveries give us two opportunities. One is to find a way to prevent injuries first, and from some of the patterns we have seen, blood clotting plays a role. There is potential and potential treatments for it. The consequences of convalescent injuries may identify subjects who will benefit from certain adjuvant treatments to protect heart function over the long term. not.”

The results of this study were limited by the nature of the patient’s choice and included only those who survived a coronavirus infection that required hospitalization.

“The convalescent patients in this study have severe COVID-19 disease and nothing about what happens to those who are not hospitalized with COVID or who are hospitalized but have no elevated troponin. The findings show potential ways to identify higher patients or suggest potential strategies that may reduce risk and improve results. More work is done. Required and MRI scans of the heart show how useful it is in investigating patients. “Elevation,” concludes Professor Fontana.

This study is also the subject of the first discussion between Professor Fontana and Professor Eike Nagel at the Annual Meeting of the Cardiovascular Magnetic Resonance Society on Friday, February 19th. Professor Nagel, director of the Cardiovascular Imaging Center at Deutsches Zentrum Für Herz-Kreislauf-Forschung (DZHK) in Frankfurt, Germany, is the lead author of a previous paper that found ongoing heart problems in up to 78% of COVID-19. .. Patients with few illnesses and most did not require hospitalization.


How does the coronavirus affect the heart?


For more information:
“Pattern of Myocardial Injury in Recovered Troponin-Positive COVID-19 Patients Assessed by Cardiovascular Magnetic Resonance”, European Heart Journal (2021). DOI: 10.1093 / eurheartj / ehab075

Valentina O. Puntmann et al. Results of cardiovascular magnetic resonance imaging in patients who recently recovered from coronavirus disease 2019 (COVID-19), JAMA Cardiology (2020). DOI: 10.1001 / jamacardio.2020.3557

Quote: Heart damage found in more than half of COVID-19 patients discharged from the hospital (February 18, 2021) can be found at https://medicalxpress.com/news/2021-02-heart-covid-patients-charged Obtained on February 18, 2021-hospital.html

This document is subject to copyright. No part may be reproduced without written permission, except for fair transactions for personal investigation or research purposes. The content is provided for informational purposes only.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]