Connect with us

Health

Pfizer reduces ultra-low temperature requirements for COVID-19 vaccine

Avatar

Published

on


According to new data submitted by Pfizer to the US Food and Drug Administration, the mRNA COVID-19 vaccine is stable for longer periods of time at warmer temperatures than previously thought. The new recommendations suggest that the vaccine is stable for 2 weeks in a freezer around -15 ° C (5 ° F), greatly increasing shipping and storage flexibility.

The first COVID-19 vaccine approved for emergency use in the United States last year was based on state-of-the-art mRNA technology. Developed by German company BioNTech with the support of pharmaceutical giant Pfizer. Vaccine showed incredible effect However, be careful. The vaccine had to be kept very cold to prevent degradation.

Standard drug freezers offer temperatures from -25 ° C to -15 ° C (-13 ° F to 5 ° F). Ultra-low temperature freezers, on the other hand, can keep items at temperatures between -80ºC and -60ºC (-112ºF to -76ºF).

The main challenge in effectively distributing Pfizer’s COVID-19 vaccine is the lack of a super cold chain delivery infrastructure in many parts of the world to keep the vaccine at the required temperature. Pfizer has developed a new dry ice package to help distribute the vaccine widely, but the requirement for ultra-low temperature storage has inevitably been a difficult and costly problem to overcome.

Currently, the company suggests that new data indicate that the vaccine is stable at more normal freezer temperatures between -25 ° C and -15 ° C (-13 ° F to 5 ° F) for at least two weeks. Claims to be. This new data was provided to the FDA in the hope of updating the Emergency Authorization details.

BioNTech CEO Ugur Sahin suggests that this new recommendation stems from ongoing stability studies that have been underway since mass production of the vaccine began late last year. The mRNA technology behind this vaccine is so new that the company has understated its storage recommendations until further data are collected.

“Our top priority was to quickly develop safe and effective vaccines and make them available to the world’s most vulnerable people to save lives,” says Sahin. “At the same time, we continuously collected data that would allow storage at approximately -20 ° C (-4 ° F). The data submitted facilitated the handling of vaccines in pharmacies and further to the vaccine center. It can provide great flexibility. “

Pfizer’s candidate is not the only mRNA COVID-19 vaccine on the market.Another shortly after Pfizer’s emergency FDA approval last year Moderna RNA vaccine, Did not require comparable ultra-low temperature storage.

Moderna’s RNA vaccine is said to be stable for up to 6 months at normal freezer temperatures from -25 ° C to -15 ° C (-13 ° F to 5 ° F). Explaining the storage condition mismatch between two similar mRNA vaccines, Moderna argues that its unique lipid nanoparticle formulation improves stability at high temperatures compared to Pfizer candidates.

Talk to NPR In November last year, a Moderna spokeswoman also explained that the company has gained significant experience over the years in the development of many other mRNA vaccines. This probably gives us a deeper insight into how stable the mRNA vaccine is at different temperature conditions.

“I don’t need it now [ultra-cold conditions] Product quality is improved, [it] It does not need to be highly frozen to avoid degradation of mRNA, “said Moderna spokeswoman Colleen Hussey.

Peter English, a former chairman of the British Medical Association’s Public Health Commission, said that as Pfizer learns over time, it may further increase the storage temperature requirements for the COVID-19 vaccine. ..

“I wouldn’t be surprised if they could increase this period over time and as the pre-test storage period increased,” says English. “This can significantly ease infrastructure requirements.”

Source: Pfizer

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]