Oral Covid Treatment Brings Promising Trial Data: Pharmaceutical Companies

German pharmaceutical giant Merck and its US partner reported promising results on Saturday, saying they could help reduce viral load in patients in a trial of a drug given orally to fight COVID-19.

“These preliminary data are encouraging when antiviral treatment needs for SARS-CoV-2 are not met,” said Wendy Painter, Ridgeback Biotherapy, Chief Medical Officer, US company. I will.

In January, Merck stopped researching two COVID vaccine candidates, but proceeded with research on two products to treat the disease, including a pill-based product called molnupiravir developed by Ridgeback Biotherapy. ..

this drag In a meeting with an infectious disease expert, Merck said it significantly reduced the patient’s viral load after five days of treatment.

This Phase 2a test (there are three stages of clinical trials before the product is approved) was conducted in 202 unhospitalized individuals with COVID-19 symptoms.

There were no safety warnings and of the four serious adverse events reported, Ridgeback said it was not considered to be related to taking the drug.

Oral antiviral drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) may be prescribed for seasonal flu, but researchers have not yet come up with a similar one to fight the coronavirus.

Results of this study — Viral load William Fischer, a principal investigator in research at the University of North Carolina and a professor of medicine, said it is promising among early-stage COVID-19 patients being treated with molnupiravir.

“If supported by additional research, (they) can have significant public health implications, especially as the SARS-CoV-2 virus continues to spread and evolve globally,” Fisher said. He added.

Merck is also working on another oral COVID treatment called MK-711.

Preliminary results from Clinical trial In January, the company showed that the risk of death or respiratory problems in patients hospitalized with moderate to severe COVID-19 was reduced by more than 50%.

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Merck Ends Development of Two Potential COVID-19 Vaccines

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© 2021 AFP

Quote: Oral Covid treatment provides promising study data: Pharmaceutical company (March 7, 2021) from https://medicalxpress.com/news/2021-03-oral-covid-treatment-yields-trial.html Obtained March 7, 2021

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