Connect with us

Health

40-year-old drug gives hope to COVID patients

40-year-old drug gives hope to COVID patients

 


Older drugs are being tested as a new early treatment potential for COVID-19. There are clues that the 40-year-old antidepressant fluvoxamine may prevent severe lung damage in COVID patients. It is currently being tested in large randomized clinical trials in the United States and Canada.

The story begins with a psychiatrist’s home illness with COVID symptoms. Dr. Angela Lersen, a psychiatrist at the University of Washington, was wondering how she could recover and help herself and others when she recalled her study with mice and fluvoxamine. This drug stopped sepsis in mice. This is a reaction of the immune system that is thought to cause damage to organs and cause runaway inflammation that can be fatal. It is believed that similar reactions can occur in patients with COVID.

Reirsen has contacted another psychiatrist, Dr. Eric Lenze, who specializes in finding new uses for drugs that have already been approved by the FDA. He immediately saw her rationale. “Angela presented a very compelling and innovative example of this drug,” he tells Alfonsi. “And we found that psychiatric drugs, such as safety and ease of use, have many properties that allow them to enter the body quickly, making them ideal for practical use.”

Renze was able to fund a small randomized clinical trial with the help of the University of Washington and Silicon Valley entrepreneur Steve Kirsch, where he worked. The test results were compelling and published in the Journal of the American Medical Association. The study included 152 patients, 80 of whom received fluvoxamine. “So the results were really incredible. Of the 80 people who received fluvoxamine, 8% of those who received placebo did not get worse,” Lenze said. Says.

The editors of JAMA were impressed, but did not recommend widespread use. They wanted confirmation in a larger test.

Alfonsi reports that night that Dr. David Seftel learned about Lenze’s work at a webinar he hosted. He takes care of hundreds of workers at the Golden Gate Fields, a thoroughbred racetrack in California. He was skeptical. โ€œI’m a natural skeptic. Immediately after the webinar, I delved deeper into science,โ€ says Seftel. “Then I saw Eric Lenze’s treatise. Because of its excellent methodology, JAMA chose from 10,000 other treatises and published it. It feels comfortable for me to take for patients. “It’s a treatise,” he tells Alfonsi. “In this particular situation, strong biochemistry, good initial clinical results, minimal downsides. I felt I had to act.”

Ceftel provided a prescription for fluvoxamine to newly diagnosed COVID patients in Golden Gate Fields.

“65 patients chose to take fluvoxamine. 48 declined,” said Seftel. “12.5% โ€‹โ€‹of those who refused fluvoxamine were hospitalized and one died. The group taking fluvoxamine was not hospitalized.” Asked that it might be a fluke, Ceftel replies, “I don’t think so. Flukes can’t affect as clever and evil viruses as COVID.” (CBS)

..

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]