Health

Studies find that the use of aspirin for cardiovascular disease may reduce the likelihood of COVID-19 infection-ScienceDaily

Aspirin is an established, safe, low-cost drug that has been commonly used for many years in the prevention and treatment of cardiovascular disease, and in the past it has been an analgesic and antipyretic. The use of aspirin was very popular decades before its activity against the RNA virus was confirmed in vitro during the 1918 Spanish flu pandemic. Studies have shown that aspirin, in addition to its well-known anti-inflammatory effect, can regulate the innate and adaptive immune responses, helping the human immune system fight several viral infections. it was done.

With this information in mind, Israeli researchers suggest that pre-infection treatment with the use of low-dose aspirin (75 mg) may have potential beneficial effects on COVID-19 susceptibility and duration of illness. I assumed. A joint team of Leumit Health Services, Bar-Ilan University, and Barzilai Medical Center conducted an observational epidemiological study using data from Leumit Health Services, Israel’s National Health Maintenance Organization.Their findings have recently been published FEBS Journal..

Researchers analyzed data from 10,477 people tested for COVID-19 during the first COVID-19 wave in Israel from February 1, 2020 to June 30, 2020. Compared to non-aspirin users, the chances of getting COVID-19 infection are 29% lower. The proportion of patients treated with aspirin was significantly lower among COVID-19-positive individuals compared to COVID-19-negative individuals. And subjects treated with aspirin were less associated with the likelihood of COVID-19 infection than those who were not. In addition, the group observed that the SARS-CoV-2 PCR test results showed significantly shorter positive-to-negative conversion times in aspirin-using COVID-positive patients, with a 2-3 day shorter disease duration in some patients. Existing conditions.

“This observation of the potential beneficial effects of low-dose aspirin on COVID-19 infection is preliminary, but seems very promising,” said Eli of Barzilai Medical Center, who led the study.・ Professor Magen said.

Dr. Eugene Merzon, Principal Investigator at Leumit Health Services, emphasized the importance of using larger samples and repeating the findings, including patients from other hospitals and countries, to validate the results. I am.

Dr. Miranafrenkel Morgenstern, School of Medicine, University of Bairan: “This study aimed to better understand the potential positive effects of aspirin in supporting the fighting COVID-19 of the human immune system. Cohort and randomized clinical trials. “

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material Provided by University of Bairan.. Note: The content can be edited in style and length.

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