The new coronavirus jumped from bats to humans without much genetic alteration: Research | Weather Channel-Weather Channel Articles

A team of researchers found that the virus SARS-CoV-2 jumped from bats to humans with little change. The latest study emphasizes that since December 2019, few “significant” genetic alterations have been observed in the sequenced viral genome during the first 11 months of the coronavirus pandemic.The results of this new study were published in the journal PLOS Biology.

Glasgow University researcher Oscar McLean said, “This does not mean that no changes have occurred, but that evolutionarily important mutations have accumulated and, like all viruses, have millions of transmissions. He said he would “surf” along with the event.

Some changes may affect you. For example, spike substitution D614G, which has been shown to enhance transmissibility, and other specific tweaks of viral biology scattered throughout its genome. But overall, the “neutral” evolutionary process dominated.

“This stagnation can be due to the highly sensitive nature of the human population to this new pathogen, which leads to exponential growth due to limited pressure from herd immunity and lack of containment. Almost every virus is the winner, “MacLean added.

“What is very surprising is how infectious SARS-CoV-2 was from the beginning. Viruses that jump to new host species are usually as capable as SARS-CoV-2 when spreading. It takes time to get the adaptation, and in most cases it does not go through that stage, resulting in dead-end spillover effects and localized outbreaks, “said Sergei L. of Temple University in the United States. Kosakovsky Pond says.

When studying the mutation process of SARS-CoV-2 and related salvecoviruses (a group of viruses in which SARS-CoV-2 belongs to the bats and pangolins), the authors found evidence of a fairly significant change. However, it was all before the appearance of SARS-CoV-. 2 for humans.

This means that the “generalist” nature of many coronaviruses and their apparent ability to jump between hosts has imbued SARS-CoV-2 with its ready-made ability to infect humans and other mammals. However, studies have shown to humans that these properties probably evolved in bats before the ripple effect.

This study is a collaborative study by researchers in the United Kingdom, the United States and Belgium.

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The above article is published from a wire source with minimal changes to headlines and text.

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