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Here’s how the signal from your muscles protects you from dementia:




Scientists at St. Jude Children’s Research Hospital are studying how different parts of the body communicate and how signals sent by skeletal muscle affect the brain.

ANI | , Washington DC

Published on IST at 7:17 pm on March 27, 2021

Scientists at St. Jude Children’s Research Hospital are studying how different parts of the body communicate and how signals sent by skeletal muscle affect the brain. The team studied state-of-the-art brain cell models called fruit flies and organoids. They focused on the signals that muscles send when stressed. Researchers have discovered that stress signals depend on an enzyme called amylase amylase and its product, the disaccharide maltose.

Scientists have shown that mimicking stress signals can protect the brain and retina from aging. The signal works by preventing the accumulation of accidentally folded protein aggregates. Research suggests that regulating this signaling may help combat neurodegenerative conditions such as age-related dementia and Alzheimer’s disease.

Dr. Fabio Demontis of St. Jude Developmental Neurobiology said, “Muscle-induced stress responses can not only affect muscles, but also promote protein quality control in distant tissues such as the brain and retina. I found it. ” “This stress response actually protected those tissues during aging.”

This story was published from a news agency feed without changing the text. Only the heading has changed.



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