High liver fat (fatty liver) associated with increased risk of hospitalization in obese COVID-19 patients

Oxford, United Kingdom-March 29, 2021. A new study published this month in Frontiers in Medicine (Gastroenterology) found that individuals with both obesity and severe fatty liver are five times more likely to require hospitalization for their illness. I am. MRI scans for research were collected using Liver MultiScan® from Perspectum, a non-invasive liver imaging technique.

Obesity is often associated with liver fat accumulation and can lead to liver disease. New data suggest that obese patients are at increased risk of developing a serious illness with COVID-19. The World Obesity Federation summarizes recent reports suggesting that nearly 50% of people hospitalized for COVID-19 in the United States are also affected by obesity. According to a new report from the CDC (Centers for Disease Control and Prevention), 78% of people who were hospitalized, ventilated, or died of COVID-19 were overweight or obese.

Imaging studies investigating whether excess liver fat can affect the severity of COVID-19 in obese individuals show that individuals with both obesity and fatty liver have COVID-19. We have shown that we are five times more likely to require hospitalization. In particular, obese people with normal liver fat were not at high risk of hospitalization.

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“Some obese people have normal levels of liver fat, while some non-obese people have high levels of liver fat. Existing liver disease is severe. It is appropriate to see if it increases the risk of COVID-19 and how it is associated with obesity, “said Perspectum, the first author and scientist to develop Liver MultiScan. This is Adriana Roca-Fernandez. “Measurement of liver fat and detection of liver disease can be achieved using non-invasive imaging methods such as Perspectum’s well-validated magnetic resonance imaging (MRI) technique, COVID at high risk of severe disease- Helps identify 19 patients. “”

Understanding the contribution of liver fat to the risks and consequences of COVID-19 is important for the clinical understanding and management of COVID-19 and long-term COVID. Roca-Fernandez et al. , 2021 also has a low male status and socioeconomic status in a study that “fatty liver, not underlying obesity, increases the risk of COVID-19 infection and hospitalization.” In addition, the study showed that participants who tested positive for COVID-19 were more likely to have high liver fat. MRI data were taken by UK Biobank, one of the world’s largest biomedical databases, prior to the COVID-19 pandemic and included 4,458 people who were later tested for COVID-19.

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