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Patients with chronic coronary syndrome, diabetes may be at increased risk of CV events




April 8, 2021

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Disclosure: Vidal-Petiot reports that he received non-financial support and personal fees from Servier in addition to the submitted work. See the survey for relevant financial disclosures of all other authors.

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Almost 30% of patients with chronic coronary syndrome have diabetes, increasing the risk of adverse consequences of CV, according to a study published in. European Journal of Preventive Cardiology.

“Diabetes was associated with worse outcomes, even in areas with the lowest prevalence. In Europe, for example, diabetes has a 29% increased risk of combined outcomes of heart attack, stroke, or cardiovascular death. It was relevant. This indicates that the management of these very high-risk patients with heart disease and diabetes needs to be improved. Countries have identified and coordinated education and coordination of these patients. You need to provide a preventive program. “ Emmanuelle Vidal-Petiot, MD,doctorate, An associate professor at the Bisha-Claude Bernard Hospital in Paris said in a press release.

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Researchers performed 32,694 analyzes Patients from the CLARIFY registry of chronic coronary syndrome From 45 countries. Of the cohort, 29% had diabetes.

Researchers have identified patients with one or more of the following criteria as having chronic coronary syndrome: MI, evidence of coronary artery stenosis greater than 50%, proven Symptomatological myocardial ischemia And previous revascularization.

In a multivariate-adjusted model, researchers found that among patients with chronic coronary syndrome, diabetes was CV death, MI or stroke (adjusted HR = 1.28; 95% CI, 1.18-1.39), all causes of death (1.18-1.39). Reported to be associated with increased risk. aHR = 1.38; 95% CI, 1.27-1.5), CV death (aHR = 1.39; 95% CI, 1.25-1.54), MI (aHR = 1.26; 95% CI, 1.1-1.43), stroke (aHR = 1.29; 95% CI, 1.09-1.52), HF hospitalization (aHR = 1.15; 95% CI, 1.03-1.28) and coronary blood circulation reconstruction (aHR = 1.14; 95% CI, 1.04-1.25).

“Obesity and lack of exercise are common risk factors for both diabetes and heart disease, and our results underscore the urgent need to improve nutrition and raise global activity levels,” Vidal said. -Petiot mentioned in the release.

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