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Remdesivir appears to be safe for seriously ill children.Patients may not pose the highest risk to hospital staff


Lab engineers will exhibit “Remdesivir”, a treatment for coronavirus disease (COVID-19), at the Eva Pharma facility in Cairo, Egypt, on June 25, 2020. REUTERS / Amr Abdallah Dalsh

The following is a summary of some of the latest scientific research on the new coronavirus and efforts to find treatments and vaccines for the virus-induced disease COVID-19.

Antiviral Remdecibir Seems Safe for Children

The antiviral drug remdesivir appears to be safe and effective in children with COVID-19 as well as adults, according to the largest study to date in children with severe COVID-19 who received this drug. ..Remdesivir sold by Gilead Sciences (GILD.O) Under the brand name Veklury, COVID-19 reduces the time to recovery for adults. Not yet approved for children under 12 years old. In March 2020, Gilead began accepting doctors’ requests for compassionate use of remdesivir in critically ill children with COVID-19. “Remdesivir was well tolerated and had a low incidence of serious adverse events,” researchers said Wednesday in pediatrics, in a new study of 77 children in the United States, United Kingdom, Italy, and Spain. Reported in. Within four weeks of starting treatment, 88% of children reduced their need for oxygen support, 83% recovered, and 73% were discharged. Of those who needed a ventilator, 90% were able to remove it. Randomized controlled trials are underway to confirm that the high levels of recovery are due to the effects of remdesivir, the researchers said. An editorial published in this study stated that “although morbidity and mortality differ, children hospitalized with acute COVID-19 often follow an adult-like disease course. Children also exhibit an adult-like remdecibyl response It’s likely. ” (((, ).

Patients may not pose the highest COVID-19 risk to hospital staff

A new study suggests that if a US healthcare worker at the forefront of a pandemic is infected with COVID-19, it is more likely to be transmitted locally than in patient care. At a major medical center in Wisconsin, researchers investigated potential sources of infection by analyzing the genetic sequences of the virus from swab samples from 95 healthcare workers and their patients. Only 11% of participants’ infections could be followed up to colleagues and only 4% to patients, the researchers reported in clinical infections. Their observations are consistent with recent studies assessing healthcare-related infections in the Netherlands and the United Kingdom, and found that the most important risk factor for COVID-19 is not the workplace factor but the proportion of illness in the surrounding area. He said it was consistent with another recent study. “Healthcare professionals appear to be most commonly infected with SARS-CoV-2 through community exposure,” the researchers conclude. “This emphasizes the continued importance of wearing masks, physical distance, strong testing programs, and rapid distribution of vaccines.” ((().

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