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Covishield protects against Indian varieties, says CCMB’s Rakesh Mishra




Preliminary results from a new study showed that the Covishield vaccine protects against the first detected B.1.617 coronavirus mutant in India, said Rakesh Mishra, director of the Center for Cellular and Molecular Biology, on Thursday. Said.

“It’s a very preliminary but encouraging result,” he said in a tweet. “Early results using the in vitro neutralization assay show that both convalescent (pre-infection) sera and Covishield vaccinated sera provide protection against the B.1.617 mutant.”

The Center for Cellular and Molecular Biology is the Institute of the Scientific and Industrial Research Council.

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The B.1.617 variant was first detected in Maharashtra in October. GISAID Global Database.. Initially, it was thought to contain two mutations, E484Q and L452R, so it was called a “double mutation” variant.

The virus constantly mutates and produces different versions or variants of the virus itself. But what scientists are worried about about B.1.617 is the presence of three mutations, E484Q, L452R, and P6814. That’s why we now call B.1.617 a “triple mutant” variant. These mutations have been found in other “mutants of concern”. This is the term currently used for mutants in the United Kingdom, South Africa and Brazil.

Despite the lack of data, there is widespread speculation among Indian scientists that the current coronavirus surge (worst since the outbreak of the pandemic) is caused by a variant of B.1.617. .. In India, more than 2 racks of coronavirus cases have been reported daily since April 15, and more than 3 racks of infection have been reported daily in the last 2 days.

The· Indian Medical Research Council Covaxin, a proprietary coronavirus vaccine, also states that it effectively neutralizes double mutants of SARS-CoV-2 and other variants. However, vaccine maker Barrat Biotech said on Tuesday that data on the efficacy of covacin against covid mutants are expected for only one week.

Covaxin was developed in collaboration with the Indian Medical Research Council, the National Institute of Virology, and Bharat Biotech. The Oxford-AstraZeneca vaccine, Covishield, is manufactured by the Serum Institute of India.

Read again:

The Indian Triple Mutant Covid variant raises global concerns. Why do we know so little about it?


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