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DNA explainer: efficacy, herd immunity

 


The country has gone through the terrible stage of the second wave of the COVID-19 pandemic. At this stage, more people are infected with the virus, and there are more serious cases that require emergency medical care and surface oxygen supply.

Looking at the situation, the government is speeding up vaccination The process in the country, and now anyone over the age of 18 is eligible to take a jab. On Monday, the federal government announced that the third phase of COVID-19 vaccination in India would begin on May 1st and that anyone over the age of 18 would be eligible for vaccination.

Experts urge people to focus less on efficacy numbers and instead prioritize vaccination with the licensed vaccines provided to them. But first, let’s understand what vaccines are effective today and what herd immunity is.

What is the effectiveness of the vaccine?

Vaccine efficacy is the rate of disease reduction in a group of people vaccinated in clinical trials. This is different from vaccine efficacy, which measures how well a vaccine works when it is given to people in non-clinical trials.

Efficacy reflects how well a vaccine works in a controlled environment such as a clinical trial. All new vaccines undergo clinical trials to test how well they work.

Vaccine candidate developers typically use clinical trial research protocols to determine the main goals of a trial. These goals are called the primary endpoint.

Scientists can calculate how well vaccine candidates work by examining the differences in new cases of disease between the placebo-treated group and the vaccine-treated group. This is a reliable source called vaccine efficacy.

The release of vaccines and other medical interventions to the general public can reduce efficacy figures.

What is herd immunity?

The term refers to when a sufficient number of people are immune to the disease so that the virus cannot be transmitted to a new host.

If the majority of the population is immune to the disease, this provides indirect protection or herd immunity (also called herd immunity or herd immunity) to people who are not immune to the disease.

Depending on the severity of the infection, 50% to 90% of the population usually requires immunity before the infection rate begins to decline.

The higher the level of immunity, the greater the benefits. Therefore, it is important to vaccinate as many people as possible.

The more people who are vaccinated, the less chance the virus will spread to the population and the closer it is to herd immunity.

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