Connect with us

Health

Johns Hopkins is developing a device for the rapid diagnosis of gonorrhea

Johns Hopkins is developing a device for the rapid diagnosis of gonorrhea

 


A team led by Johns Hopkins University has created an inexpensive portable device and mobile phone app to diagnose gonorrhea in less than 15 minutes and determine if a particular strain responds to front-line antibiotics.

The present invention improves on conventional trials in hospital laboratories and clinics, which usually take up to a week to produce results, during which the patient can unknowingly spread the infection.Team results today Scientific translation medicine..

“Our portable and inexpensive test platform has the potential to change the game in that it enables the diagnosis and rapid treatment of sexually transmitted diseases,” said a professor of mechanical engineering at the core of the Nanobiotechnology Institute. Researcher and team leader Tza-Huei Wang said. At Johns Hopkins Whiting School of Engineering. “This improves clinical outcomes because patients can be diagnosed on the fly and treatment can begin immediately. This is a resource that is not always available to all patients in a well-equipped laboratory. Especially valuable in a low-lying environment. “

More than 87 million people worldwide are infected with gonorrhea. Gonorrhea increases resistance to antibiotics and can lead to catastrophic sexually transmitted infections. Experts say that rapid identification and treatment of infected individuals is the only way to prevent a surge in the number of cases and a further increase in antibiotic-resistant strains.

The Wang team’s device, called PROMPT (Portable, High Speed, On-Cartridge, Magnetohydrodynamic Purification and Testing Platform), runs on a simple 5-volt battery and includes a thermoplastic cartridge for about $ 2.

The test is easy. A cotton swab containing the patient’s body fluid is mixed with the solution of magnetic particles in the tube and the droplets of that blend are loaded into the cartridge. The cartridge snaps to the device. The device transfers the magnetized particles to the reagents in the cartridge. The cartridge runs a 40-cycle polymerase chain reaction (PCR) test before displaying the results on the mobile phone screen. (PCR testing allows scientists to take small samples of DNA and amplify them for further study, for example, the gold standard for testing COVID-19.)

During tests from sexual health clinics in Baltimore and Kampara, Uganda, PROMPT correctly detected the most common gonorrhea strains in about 97% of the time. It was 100% accurate to determine whether a tested strain of gonorrhea responded to ciprofloxacin, a drug that targets infections resistant to other antibiotics.

“Our tests maintain the same sensitivity and specificity that are currently used in hospital and clinic laboratories, but reduce the associated costs and time,” said Johns of Biomedical Engineering. Alex Trick, a team member who is a Hopkins graduate student, said. “We want these diagnoses to be available to everyone who needs them, when they need them.”

Wang and his team form a college spin-off for regulatory approval, manufacturing, and distribution.

“We expect to be able to deliver these products to those who can really benefit in a couple of years,” he said.

###

At Johns Hopkins, other team members include Charlotte Gades, Elizabeth A. Gilliams, Matthew M. Hamil, Yukari Manabe, Johann H. Melendez, and Yushanche of the School of Medicine. Liben Chen, Department of Mechanical Engineering, Whiting School.

The project was supported by a grant from the National Institutes of Health.

Disclaimer: AAAS and Eurek Alert! We are not responsible for the accuracy of news releases posted to EurekAlert! To use the information by contributing to the institution or through the Eurek Alert system.

..

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]