Health
Delaying the second dose of Covid vaccine under age 65 may reduce mortality: study
According to a study published by the BMJ, these conditions include ≥80% single-dose vaccine efficacy (efficacy) and a daily vaccination rate of 0.1% to 0.3% of the population. ..
If these conditions are true, the study states that the strategy can prevent 47 to 26 deaths per 100,000 people, respectively.
“Decision makers need to consider local vaccination rates and weigh the benefits of increasing these rates by delaying the second vaccination against the risks associated with the remaining uncertainty of this strategy. “There is,” writes researchers, including Thomas C. Kingsley, an assistant professor of medicine. Mayo Clinic, Minnesota.
“These decisions should continue to be reassessed as new data become available,” the researchers added.
Both Pfizer The standard double-dose Schedule Modernacovid-19 vaccine is very effective in preventing symptomatological infections and death. However, due to low vaccination rates, immunity around the world remains low.
The longer it takes to effectively vaccinate the world’s population, the higher the risk of developing vaccine-resistant strains. This has led to a call to prioritize single dose vaccination for as many people as possible, even if this means delaying a second dose beyond the time frame studied.
“The justification for this relies on the assumption that meaningful protection against Covid-19 can be achieved after a single dose of the vaccine, which is the subject of intense debate,” the team said.
To further investigate this, they set out to measure the impact of delayed double-dose vaccine policies on infection, hospitalization, and death compared to the current scheduled double-dose regimen. The team ran a series of scenarios over a six-month period using a simulation model based on a “real” sample population of 100,000 adults in the United States.
The results suggest that a delayed double vaccination strategy is optimal for vaccination rates with a daily population of 0.3% or less when the vaccine efficacy of a single vaccination is 80% or higher.
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