Two common food colorings may be associated with symptoms of inflammatory bowel disease

Certain food colorings may play a role in causing the symptoms of inflammatory bowel disease (IBD), new research, completed In the mouse I will propose. The study found that yellow and red food coloring can cause chronic intestinal inflammation in mice, but only if the immune system is already dysfunctional. The findings need further investigation, It can have some important implications for the treatment and management of patients with IBD, and its symptoms are often caused by certain foods and drinks.

People with IBD have prolonged episodes of intestinal inflammation that can cause symptoms such as diarrhea, fever, and painful cramps to recur. The exact cause of IBD is still a mystery, but genetics and an imbalanced immune system are known to be the major causes of IBD symptoms. One of the components of the immune system that is often associated with IBD High levels of protein known as interleukin-23 (IL-23), and some treatments for IBD Tuck it up..

Researchers at Mount Sinai School of Medicine have worked with mice designed to have dysregulated IL-23, as seen in some IBD patients.But their Previous research Simply too much IL-23 has been shown to be insufficient for mice to begin developing colitis and chronic inflammation of the colon.It was only after feeding them a specific diet A diet in which a mouse becomes ill. And after examining specific parts of the diet, researchers theorized that two common food colorings, Red 40 and Yellow 6, could be stimulating ingredients...

Their new research, Release In cell metabolism Thursday seems to indicate that they were right. They developed colitis when they fed these mice with dye-containing food or water. However, no similar effect was seen when healthy control mice were fed these dyes, or dysregulated mice were fed a diet free of either dye.

“Our research reveals that food colorants contribute to the development of colitis in a condition characterized by increased IL-23 signaling,” they write.

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IBD is a complex condition. And not just IL-23 Criminal It is believed to increase the risk of having IBD episodes. These new discoveries, which the author warns, should also be confirmed by people before confirming that there is a real link between IBD and food coloring consumption. However, if this link is confirmed, it can certainly affect the care of IBD patients. Some people in IBD report it specific Food and drink Increases their chances of experiencing flare-ups. And when these food colorings are involved as triggers, Red 40 and Yellow 6 are found in so many products that they can have a significant impact on people’s diets. Both are commonly used in pharmaceutical packaging.

“Dramatic changes in air and water pollutant concentrations in the human diet of the last century and increased use of processed foods and food additives correlate with increased incidence of inflammatory and autoimmune diseases. “Masu,” said senior author Sergio Rila.Researcher at the Institute of Precision Immunology, Mount Sinai School of Medicine statement Released by the school. “These environmental changes are thought to contribute to the development of these diseases, but relatively little is known about how they occur. This study found that food colors help human health. I hope it will be a step towards understanding the impact. “

In addition to studying people with IBD, researchers have identified several species of bacteria that appear to degrade mouse pigments, so further to study the role of the gut microbiota associated with this link. He states that he can do a lot of research.

More: Common yeasts can cause problems in patients with Crohn’s disease

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