Health
60% Objective Response Rate Demonstrated in Advanced Melanoma Treatment Studies — Precision Vaccination
.jpg "60% Objective Response Rate Demonstrated in Advanced Melanoma Treatment Studies — Precision Vaccination")
Based in Norway Ultimovacs ASA We announced the universal cancer vaccine today, UV1Showed an objective response rate (ORR) of 60% in metastatic melanoma in combination with the checkpoint inhibitor pembrolizumab.
All patients in this Phase 1 study have been observed for at least 18 months with a median observation period of 21 months.
60% ORR of 30% CR (6 complete response (CR); 6 partial response (PR) from a cohort of 20 patients) was the response rate of pembrolizumab alone in advanced melanoma (33-37% ORR and It clearly exceeds 5-12). % CR).
The median progression-free survival for UV1 / pembrolizumab combination therapy in this study was 18.9 months, compared with pembrolizumab alone for advanced melanoma of 5.5 to 11.6 months. Overall survival is 80%, and median overall survival has not yet been reached after 21 months of follow-up.
“These extremely powerful and exciting data further strengthen the foundation of UV1’s broader Phase II clinical program,” Ultimovacs Chief Medical Officer Jens Bjørheim commented in a press statement.
“Our development strategy shows that UV1 can significantly improve therapeutic efficacy in a wide range of indications and combinations, as it is safe and tolerated in combination with pembrolizumab and exhibits this level of beneficial clinical response. Is emphasized. “
According to the company, ” UV1 Patients with advanced malignant melanoma often lack the associated T cells to benefit permanently from pembrolizumab alone. UV1 enlarges T cells, which can increase the breadth and diversity of the immune response to all parts of the tumor.
The data is from the Ultimovacs open-label Phase I trial (NCT03538314) and will be presented as a poster presentation that will take place virtually from Friday, June 4, 2021 to Tuesday, June 8, 2021. The data show that the combination of UV1 / pembrolizumab is well tolerated and adverse events are primarily limited to low-grade effects such as injection site reactions.
Ultimovacs Founded in 2011, its proprietary technology is based on clinical research conducted at the University of Oslo Hospital. The company is a limited liability company listed on the Oslo Stock Exchange in Norway.
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
Pictures Credit
to request, modification Contact us at Here or [email protected]
 |
 |
 |
